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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Net loss from continuing operations $ (28,150) $ (22,017)
Adjustment to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization expense 304 340
Non-cash stock-based compensation 1,334 3,878
Change in fair value of common stock warrants 982 (13,174)
Change in fair value of contingent consideration (69) 59
Changes in operating assets and liabilities:    
Prepaid expenses and other assets (26) (348)
Accounts payable (648) 54
Accrued expenses and other current liabilities (1,556) 2,465
Net cash used in continuing operating activities (27,829) (28,743)
Net loss from discontinued operations 16,074 6,633
Impairment of assets held for sale 8,071 0
Changes in operating assets and liabilities attributable to discontinued operations 2,956 3,241
Net cash used in discontinued operating activities (5,047) (3,392)
Net cash used in operating activities (32,876) (32,135)
Cash flows from investing activities:    
Change in restricted cash (201)  
Cash paid for acquisition of GALE-401 rights 0 (2,315)
Cash paid for purchase of equipment and furnishings (81) (48)
Net cash used in continuing investing activities (282) (2,363)
Net cash used in discontinued investing activities (534) (3,056)
Net cash used in investing activities (816) (5,419)
Cash flows from financing activities:    
Net proceeds from issuance of common stock 47,416 0
Net proceeds from exercise of stock options 31 4,342
Proceeds from exercise of warrants 0 10,717
Proceeds from common stock issued in connection with ESPP 309 263
Principle payments on long-term debt (2,902) (908)
Net cash provided by financing activities 44,854 14,414
Net increase (decrease) in cash and cash equivalents 11,162 (23,140)
Cash and cash equivalents at the beginning of period 23,650 47,787
Cash and cash equivalents at end of period 34,812 24,647
Supplemental disclosure of cash flow information:    
Cash received during the periods for interest 12 13
Cash paid during the periods for interest 437 632
Supplemental disclosure of non-cash investing and financing activities:    
Fair value of warrants issued in connection with common stock recorded as cost of equity $ 10,296 27,026
Reclassification of warrant liabilities upon exercise   $ (27,020)