    <SEC-DOCUMENT>0001390478-15-000049-index.html : 20151110
    <SEC-HEADER>0001390478-15-000049.hdr.sgml : 20151110
    <ACCEPTANCE-DATETIME>20151109164624
    ACCESSION NUMBER:		0001390478-15-000049
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		25
    CONFORMED PERIOD OF REPORT:	20151109
    ITEM INFORMATION:		Results of Operations and Financial Condition
    ITEM INFORMATION:		Regulation FD Disclosure
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20151109
    DATE AS OF CHANGE:		20151109

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Galena Biopharma, Inc.
    		CENTRAL INDEX KEY:			0001390478
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-33958
    		FILM NUMBER:		151216314

    	BUSINESS ADDRESS:
    		STREET 1:		4640 SW MACADAM AVENUE
    		STREET 2:		SUITE 270
    		CITY:			PORTLAND
    		STATE:			OR
    		ZIP:			97239
    		BUSINESS PHONE:		855 855 GALE

    	MAIL ADDRESS:
    		STREET 1:		4640 SW MACADAM AVENUE
    		STREET 2:		SUITE 270
    		CITY:			PORTLAND
    		STATE:			OR
    		ZIP:			97239

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	RXi Pharmaceuticals Corp
    		DATE OF NAME CHANGE:	20110926

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	GALENA BIOPHARMA, INC.
    		DATE OF NAME CHANGE:	20110922

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	RXI PHARMACEUTICALS CORP
    		DATE OF NAME CHANGE:	20110921
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>8-K
    <SEQUENCE>1
    <FILENAME>gale-201511098xk.htm
    <DESCRIPTION>8-K
    <TEXT>
    Document 1 - file: gale-201511098xk.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.1
    <SEQUENCE>2
    <FILENAME>gale-20151109ex991.htm
    <DESCRIPTION>EXHIBIT 99.1
    <TEXT>
    Document 2 - file: gale-20151109ex991.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.2
    <SEQUENCE>3
    <FILENAME>q32015earningsslides.htm
    <DESCRIPTION>EXHIBIT 99.2
    <TEXT>
    Document 3 - file: q32015earningsslides.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>prgraphic05072015pa02.jpg
    <TEXT>
    Document 4 - file: prgraphic05072015pa02.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>q32015earningsslides001.jpg
    <TEXT>
    Document 5 - file: q32015earningsslides001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>q32015earningsslides002.jpg
    <TEXT>
    Document 6 - file: q32015earningsslides002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>q32015earningsslides003.jpg
    <TEXT>
    Document 7 - file: q32015earningsslides003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>q32015earningsslides004.jpg
    <TEXT>
    Document 8 - file: q32015earningsslides004.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>q32015earningsslides005.jpg
    <TEXT>
    Document 9 - file: q32015earningsslides005.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>q32015earningsslides006.jpg
    <TEXT>
    Document 10 - file: q32015earningsslides006.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>q32015earningsslides007.jpg
    <TEXT>
    Document 11 - file: q32015earningsslides007.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>q32015earningsslides008.jpg
    <TEXT>
    Document 12 - file: q32015earningsslides008.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>q32015earningsslides009.jpg
    <TEXT>
    Document 13 - file: q32015earningsslides009.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>q32015earningsslides010.jpg
    <TEXT>
    Document 14 - file: q32015earningsslides010.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>q32015earningsslides011.jpg
    <TEXT>
    Document 15 - file: q32015earningsslides011.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>q32015earningsslides012.jpg
    <TEXT>
    Document 16 - file: q32015earningsslides012.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>q32015earningsslides013.jpg
    <TEXT>
    Document 17 - file: q32015earningsslides013.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>q32015earningsslides014.jpg
    <TEXT>
    Document 18 - file: q32015earningsslides014.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>q32015earningsslides015.jpg
    <TEXT>
    Document 19 - file: q32015earningsslides015.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>20
    <FILENAME>q32015earningsslides016.jpg
    <TEXT>
    Document 20 - file: q32015earningsslides016.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>21
    <FILENAME>q32015earningsslides017.jpg
    <TEXT>
    Document 21 - file: q32015earningsslides017.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>22
    <FILENAME>q32015earningsslides018.jpg
    <TEXT>
    Document 22 - file: q32015earningsslides018.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>23
    <FILENAME>q32015earningsslides019.jpg
    <TEXT>
    Document 23 - file: q32015earningsslides019.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>24
    <FILENAME>q32015earningsslides020.jpg
    <TEXT>
    Document 24 - file: q32015earningsslides020.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>25
    <FILENAME>q32015earningsslides021.jpg
    <TEXT>
    Document 25 - file: q32015earningsslides021.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>