    <SEC-DOCUMENT>0001390478-16-000109-index.html : 20160510
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    <ACCEPTANCE-DATETIME>20160510163946
    ACCESSION NUMBER:		0001390478-16-000109
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		23
    CONFORMED PERIOD OF REPORT:	20160510
    ITEM INFORMATION:		Results of Operations and Financial Condition
    ITEM INFORMATION:		Regulation FD Disclosure
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20160510
    DATE AS OF CHANGE:		20160510

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Galena Biopharma, Inc.
    		CENTRAL INDEX KEY:			0001390478
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-33958
    		FILM NUMBER:		161636334

    	BUSINESS ADDRESS:
    		STREET 1:		4640 SW MACADAM AVENUE
    		STREET 2:		SUITE 270
    		CITY:			PORTLAND
    		STATE:			OR
    		ZIP:			97239
    		BUSINESS PHONE:		855 855 GALE

    	MAIL ADDRESS:
    		STREET 1:		4640 SW MACADAM AVENUE
    		STREET 2:		SUITE 270
    		CITY:			PORTLAND
    		STATE:			OR
    		ZIP:			97239

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	RXi Pharmaceuticals Corp
    		DATE OF NAME CHANGE:	20110926

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	GALENA BIOPHARMA, INC.
    		DATE OF NAME CHANGE:	20110922

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	RXI PHARMACEUTICALS CORP
    		DATE OF NAME CHANGE:	20110921
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>8-K
    <SEQUENCE>1
    <FILENAME>gale-201605108xk.htm
    <DESCRIPTION>8-K
    <TEXT>
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    <DOCUMENT>
    <TYPE>EX-99.1
    <SEQUENCE>2
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    <DESCRIPTION>EXHIBIT 99.1
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