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Stockholders' Equity (Additional Information) (Details) - USD ($)
 6 Months Ended
Feb. 13, 2017
Dec. 04, 2015
Nov. 18, 2014
May 24, 2013
Jun. 30, 2017
Jun. 30, 2016
Feb. 06, 2017
Dec. 31, 2016
Jul. 29, 2016
Jun. 28, 2016
May 10, 2016
Jan. 12, 2016
May 08, 2013
Class of Stock [Line Items]                          
Preferred stock, shares authorized         5,000,000     5,000,000          
Preferred stock, par value (usd per share)         $ 0.0001     $ 0.0001          
Common stock, shares authorized         350,000,000     350,000,000          
Common stock, par value (usd per share)         $ 0.0001     $ 0.0001          
Proceeds from Issuance or Sale of Equity         $ 5,000 $ 78,000              
Exercise price (usd per share)         $ 79.40     $ 79.40 $ 8.60 $ 8.60 $ 30.20   $ 49.40
Lincoln Park Capital, LLC Purchase Agreement                          
Class of Stock [Line Items]                          
Proceeds from Issuance or Sale of Equity     $ 4,900,000                    
Purchase Agreement Term     36 months                    
Stock issued during period related to purchase of assets     125,000                    
Share Price     $ 40.00                    
Remaining authorized repurchase amount             $ 2,100,000            
MLV & Co. LLC and Maxim Group LLC                          
Class of Stock [Line Items]                          
Remaining authorized repurchase amount   $ 19,100,000                      
Percentage of gross proceeds       3.00%                  
At Market Issuance Sales Agreements, Maximum Gross Proceeds   $ 20,000,000   $ 20,000,000                  
Common Stock | Lincoln Park Capital, LLC Purchase Agreement                          
Class of Stock [Line Items]                          
Proceeds from Issuance or Sale of Equity     $ 50,000,000                    
Issuance of common stock, shares     31,561                    
Common Stock | Underwritten Public Offering                          
Class of Stock [Line Items]                          
Issuance of common stock, shares 17,000,000                        
Exercise price (usd per share) $ 1.10                        
Proceeds From Issuance or Sale of Equity, Net Underwriting Discounts, Commissions and Offering Expenses $ 15,500,000                        
Stock purchase price per share (usd per share)                       $ 1.00  
New warrants issued during period (in shares) 17,000,000                        
Class Of Warrant Or Right, Issued, Fair Value $ 10,400,000                        
Minimum | Lincoln Park Capital, LLC Purchase Agreement                          
Class of Stock [Line Items]                          
Authorized amount in stock repurchase program             55,000,000            
Maximum | Lincoln Park Capital, LLC Purchase Agreement                          
Class of Stock [Line Items]                          
Authorized amount in stock repurchase program             $ 15,600,000