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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended | 12 Months Ended
--- | --- | --- | ---
Jun. 30, 2017 | Jun. 30, 2016 | Jun. 30, 2017 | Jun. 30, 2016 | Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2014
Operating expenses: |  |  |  |  |  |  |
Research and development | $ 2,044 | $ 6,175 | $ 4,406 | $ 11,618 | $ 19,860 | $ 23,611 | $ 27,674
General and administrative | 2,867 | 3,117 | 5,593 | 6,642 | 12,007 | 10,609 | 16,226
Total operating expenses | 4,911 | 9,292 | 9,999 | 18,260 | 31,867 | 34,220 | 43,900
Operating loss | (4,911) | (9,292) | (9,999) | (18,260) | (31,867) | (34,220) | (43,900)
Non-operating income (expense): |  |  |  |  |  |  |
Litigation settlements | (1,300) | (1,800) | (1,300) | (1,800) | (2,750) | (5,282) | 0
Change in fair value of warrants potentially settleable in cash | (185) | 14,392 | 3,707 | 10,520 | 22,220 | 1,162 | 16,556
Interest expense, net | (687) | (519) | (1,660) | (611) | (3,508) | (760) | (1,110)
Change in fair value of the contingent purchase price liability | (19) | 5,497 | (132) | 5,327 | 5,047 | 509 | 170
Total non-operating income (expense), net | (2,191) | 17,570 | 615 | 13,436 | 21,009 | (4,371) | 15,616
Income (loss) from continuing operations from continuing operations before income taxes | (7,102) | 8,278 | (9,384) | (4,824) | (10,858) | (38,591) | (28,284)
Income tax expense |  |  |  |  | 243 | 365 | 0
Income (loss) from continuing operations | (7,102) | 8,278 | (9,384) | (4,824) | (11,101) | (38,956) | (28,284)
Loss from discontinued operations | (1,302) | (2,889) | (10,738) | (6,280) | (12,448) | (24,946) | (8,322)
Net income (loss) | $ (8,404) | $ 5,389 | $ (20,122) | $ (11,104) | $ (23,549) | $ (63,902) | $ (36,606)
Net income (loss) per common share, basic: |  |  |  |  |  |  |
Basic net income (loss) per share, continuing operations (in dollars per share) | $ (0.19) | $ 0.91 | $ (0.29) | $ (0.13) |  |  |
Basic net loss per share, discontinued operations (in dollars per share) | (0.03) | (0.32) | (0.34) | (0.17) |  |  |
Basic net income (loss) per share (in dollars per share) | $ (0.22) | $ 0.59 | $ (0.63) | $ (0.30) |  |  |
Net loss per common share: |  |  |  |  |  |  |
Basic and diluted per share, continuing operations (usd per share) |  |  |  |  | $ (1.11) | $ (5.02) | $ (4.74)
Basic and diluted loss per share, discontinued operations (usd per share) |  |  |  |  | (1.25) | (3.21) | (1.39)
Basic and diluted net loss per share (usd per share) |  |  |  |  | $ (2.36) | $ (8.23) | $ (6.13)
Weighted-average common shares outstanding, basic (in shares) | 37,421,273 | 9,101,730 | 31,944,243 | 9,035,173 |  |  |
Weighted-average common shares outstanding: basic and diluted |  |  |  |  | 9,958,802 | 7,763,236 | 5,969,418
Net income (loss) per common share, diluted: |  |  |  |  |  |  |
Diluted net income (loss) per share, continuing operations (in dollars per share) | $ (0.19) | $ 0.90 | $ (0.29) | $ (0.13) |  |  |
Diluted net loss per share, discontinued operations (in dollars per share) | (0.03) | (0.32) | (0.34) | (0.17) |  |  |
Diluted net income (loss) per share (in dollars per share) | $ (0.22) | $ 0.58 | $ (0.63) | $ (0.30) |  |  |
Weighted-average common shares outstanding, diluted (in shares) | 37,421,273 | 9,273,867 | 31,944,243 | 9,035,173 |  |  |

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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Net Income -URI http://asc.fasb.org/extlink&oid=51831255 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=66902209&loc=d3e3602-108585 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 942 -SubTopic 225 -Section S99 -Paragraph 1 -Subparagraph (SX 210.9-04(22)) -URI http://asc.fasb.org/extlink&oid=6879574&loc=d3e536633-122882 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 944 -SubTopic 225 -Section S99 -Paragraph 1 -Subparagraph (SX 210.7-04(18)) -URI http://asc.fasb.org/extlink&oid=6879464&loc=d3e573970-122913 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Other Comprehensive Income -URI http://asc.fasb.org/extlink&oid=51831270 Reference 7: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03(20)) -URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688 + Details
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- Definition The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 730 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6420194&loc=d3e21568-108373 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 985 -SubTopic 20 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6501960&loc=d3e128462-111756 + Details
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