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CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS EQUITY - USD ($) $ in Thousands | Total | Settled Litigation | Senior Secured Debentures Senior Notes [Member] | Common Stock | Common Stock Settled Litigation | Additional Paid-In Capital | Additional Paid-In Capital Settled Litigation | Additional Paid-In Capital Senior Secured Debentures Senior Notes [Member] | Accumulated Deficit | Treasury Stock | Treasury Stock Settled Litigation | Treasury Stock Senior Secured Debentures Senior Notes [Member]
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Beginning balance, shares at Dec. 31, 2013 |  |  |  | 5,505,035 |  |  |  |  |  |  |  |
Beginning balance at Dec. 31, 2013 | $ 5,886 |  |  | $ 10 |  | $ 188,600 |  |  | $ (178,875) | $ (3,849) |  |
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock, shares |  |  |  | 331,650 |  |  |  |  |  |  |  |
Issuance of common stock | 10,705 |  |  | $ 1 |  | 10,704 |  |  |  |  |  |
Issuance of common stock under milestone achievement, shares |  |  |  | 219,061 |  |  |  |  |  |  |  |
Issuance of common stock under milestone achievement | 9,340 |  |  |  |  | 9,340 |  |  |  |  |  |
Issuance of common stock upon exercise of warrants, shares |  |  |  | 273,351 |  |  |  |  |  |  |  |
Issuance of common stock upon exercise of warrants | 37,742 |  |  | $ 1 |  | 37,741 |  |  |  |  |  |
Issuance of common stock in connection with employee stock purchase plan, shares |  |  |  | 5,732 |  |  |  |  |  |  |  |
Issuance of common stock in connection with employee stock purchase plan | 263 |  |  |  |  | 263 |  |  |  |  |  |
Stock based compensation for directors and employees | 5,253 |  |  |  |  | 5,253 |  |  |  |  |  |
Stock based compensation for services | 134 |  |  |  |  | 134 |  |  |  |  |  |
Exercise of stock options, shares |  |  |  | 172,488 |  |  |  |  |  |  |  |
Exercise of stock options | 4,342 |  |  |  |  | 4,342 |  |  |  |  |  |
Net loss | (36,606) |  |  |  |  |  |  |  | (36,606) |  |  |
Ending balance, shares at Dec. 31, 2014 |  |  |  | 6,507,317 |  |  |  |  |  |  |  |
Ending balance at Dec. 31, 2014 | 37,059 |  |  | $ 12 |  | 256,377 |  |  | (215,481) | (3,849) |  |
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock, shares |  |  |  | 1,607,934 |  |  |  |  |  |  |  |
Issuance of common stock | 47,416 |  |  | $ 3 |  | 47,413 |  |  |  |  |  |
Common stock warrants issued | (10,296) |  |  |  |  | (10,296) |  |  |  |  |  |
Issuance of common stock in connection with employee stock purchase plan, shares |  |  |  | 11,566 |  |  |  |  |  |  |  |
Issuance of common stock in connection with employee stock purchase plan | 309 |  |  |  |  | 309 |  |  |  |  |  |
Stock based compensation for directors and employees | 2,896 |  |  |  |  | 2,896 |  |  |  |  |  |
Exercise of stock options, shares |  |  |  | 2,270 |  |  |  |  |  |  |  |
Exercise of stock options | 31 |  |  |  |  | 31 |  |  |  |  |  |
Net loss | (63,902) |  |  |  |  |  |  |  | (63,902) |  |  |
Ending balance, shares at Dec. 31, 2015 |  |  |  | 8,129,087 |  |  |  |  |  |  |  |
Ending balance at Dec. 31, 2015 | 13,513 |  |  | $ 15 |  | 296,730 |  |  | (279,383) | (3,849) |  |
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock, shares |  |  |  | 2,872,803 |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, Other |  |  |  |  | 206,903 |  |  |  |  |  |  |
Issuance of common stock | 33,534 |  |  | $ 0 |  | 33,534 |  |  |  |  |  |
Stock Issued During Period, Value, Other |  | $ 557 |  |  | $ 0 |  | $ 557 |  |  |  | $ 0 |
Common stock warrants issued | (9,886) |  |  |  |  | (9,886) |  |  |  |  |  |
Stock issued during period to satisfy principal and interest on long-term debt, new shares |  |  |  | 3,981,208 |  |  |  |  |  |  |  |
Issuance of common stock to satisfy principal and interest of long-term debt | 8,079 |  |  | $ 0 |  | 8,079 |  |  |  |  |  |
Common stock warrants issued in connection with debt financing |  |  | $ 1,139 |  |  |  |  | $ 1,139 |  |  |  | $ 0
Issuance of common stock upon exercise of warrants, shares |  |  |  | 20,403 |  |  |  |  |  |  |  |
Issuance of common stock upon exercise of warrants | $ 95 |  |  | $ 0 |  | 95 |  |  |  |  |  |
Issuance of common stock in connection with employee stock purchase plan, shares | 29,070 |  |  | 5,477 |  |  |  |  |  |  |  |
Issuance of common stock in connection with employee stock purchase plan | $ 2,650 |  |  |  |  | 2,650 |  |  |  |  |  |
Stock based compensation for directors and employees | $ 2,264 |  |  |  |  | 2,264 |  |  |  |  |  |
Exercise of stock options, shares | 8,000 |  |  | 8,342 |  |  |  |  |  |  |  |
Exercise of stock options | $ 261 |  |  |  |  | 261 |  |  |  |  |  |
Net loss | (23,549) |  |  |  |  |  |  |  | (23,549) |  |  |
Ending balance, shares at Dec. 31, 2016 |  |  |  | 15,224,223 |  |  |  |  |  |  |  |
Ending balance (Scenario, Previously Reported [Member]) at Dec. 31, 2016 |  |  |  | $ 15 |  | 335,423 |  |  |  |  |  |
Ending balance at Dec. 31, 2016 | 28,657 |  |  | $ 2 |  | 335,436 |  |  | (302,932) | (3,849) |  |
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, Other |  |  |  | 17,000,000 |  |  |  |  |  |  |  |
Stock Issued During Period, Value, Other | 15,524 |  |  | $ 2 |  | 15,522 |  |  |  |  |  |
Common stock warrants issued | (10,357) |  |  |  |  | (10,357) |  |  |  |  |  |
Issuance of common stock upon exercise of warrants, shares |  |  |  | 5,150,660 |  |  |  |  |  |  |  |
Issuance of common stock upon exercise of warrants | 4,913 |  |  |  |  | 4,913 |  |  |  |  |  |
Issuance of common stock in connection with employee stock purchase plan, shares |  |  |  | 4,048 |  |  |  |  |  |  |  |
Issuance of common stock in connection with employee stock purchase plan | 5 |  |  |  |  | 5 |  |  |  |  |  |
Stock based compensation for directors and employees | $ 425 |  |  |  |  | 425 |  |  |  |  |  |
Fair value of common stock in exchange for services, shares |  |  |  | 90,343 |  |  |  |  |  |  |  |
Exercise of stock options, shares | 0 |  |  |  |  |  |  |  |  |  |  |
Fair value of common stock in exchange for services | $ 82 |  |  |  |  | 82 |  |  |  |  |  |
Net loss | (20,122) |  |  |  |  |  |  |  | (20,122) |  |  |
Ending balance, shares at Jun. 30, 2017 |  |  |  | 37,469,274 |  |  |  |  |  |  |  |
Ending balance at Jun. 30, 2017 | $ 19,127 |  |  | $ 4 |  | $ 346,026 |  |  | $ (323,054) | $ (3,849) |  |

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