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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2016
Income Tax Disclosure [Abstract]  
Components of Federal and State Income Tax Expense (Benefit)

The components of federal and state income tax expense are as follows (in thousands):

 

     As of December 31,  
     2016      2015      2014  

Current

        

Federal

   $ —        $ —        $ —    

State

     —          —          —    
  

 

 

    

 

 

    

 

 

 

Total current

     —          —          —    

Deferred expense

        

Federal

     210        332        —    

State

     33        33        —    
  

 

 

    

 

 

    

 

 

 

Total deferred

     243        365        —    
  

 

 

    

 

 

    

 

 

 

Total income tax expense

   $ 243      $ 365      $ —    
  

 

 

    

 

 

    

 

 

 

 

 

Components of Net Deferred Tax Assets

The components of net deferred tax assets are as follows (in thousands):

 

     As of December 31,  
     2016      2015  

Net operating loss carryforwards

   $ 97,168      $ 75,221  

Tax credit carryforwards

     4,083        3,866  

Stock based compensation

     5,757        5,050  

Other

     58        1,430  

Licensing deduction deferral

     10,263        9,910  
  

 

 

    

 

 

 

Gross deferred tax assets

     117,329        95,477  

Valuation allowance

     (117,329      (95,477
  

 

 

    

 

 

 

Net deferred tax asset

   $ —        $ —    
  

 

 

    

 

 

 

 

Components of Net Deferred Tax Liabilities

The components of net deferred tax liabilities are as follows (in thousands):

 

     As of December 31,  
     2016      2015  

In-process research and development not subject to future amortization for tax purposes

   $ 5,661      $ 5,418  
  

 

 

    

 

 

 

Gross deferred tax liability

   $ 5,661      $ 5,418  
  

 

 

    

 

 

 

 

Schedule of Provision Computed by Applying Federal Statutory Rate

The provision for income taxes differs from the provision computed by applying the federal statutory rate to net loss before income taxes as follows (in thousands):

 

     As of December 31,  
     2016      2015      2014  

Expected federal income tax benefit

   $ (7,977    $ (21,603    $ (12,447

State income taxes after credits

     (1,575      (2,375      (1,283

Unrealized gain on marketable securities

     —          —          —    

Changes in warrant value

     (8,728      (456      (6,503

Stock compensation

     (1,782      508        3,996  

Effect of change in valuation allowance

     21,852        24,029        17,275  

Income tax credits

     (217      (276      (42

Other

     (1,330      538        (996
  

 

 

    

 

 

    

 

 

 
   $ 243      $ 365      $ —