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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Operating expenses:              
Research and development $ 2,044 $ 6,175 $ 4,406 $ 11,618 $ 19,860 $ 23,611 $ 27,674
General and administrative 2,867 3,117 5,593 6,642 12,007 10,609 16,226
Total operating expenses 4,911 9,292 9,999 18,260 31,867 34,220 43,900
Operating loss (4,911) (9,292) (9,999) (18,260) (31,867) (34,220) (43,900)
Non-operating income (expense):              
Litigation settlements (1,300) (1,800) (1,300) (1,800) (2,750) (5,282) 0
Change in fair value of warrants potentially settleable in cash (185) 14,392 3,707 10,520 22,220 1,162 16,556
Interest expense, net (687) (519) (1,660) (611) (3,508) (760) (1,110)
Change in fair value of the contingent purchase price liability (19) 5,497 (132) 5,327 5,047 509 170
Total non-operating income (expense), net (2,191) 17,570 615 13,436 21,009 (4,371) 15,616
Income (loss) from continuing operations from continuing operations before income taxes (7,102) 8,278 (9,384) (4,824) (10,858) (38,591) (28,284)
Income tax expense         243 365 0
Income (loss) from continuing operations (7,102) 8,278 (9,384) (4,824) (11,101) (38,956) (28,284)
Loss from discontinued operations (1,302) (2,889) (10,738) (6,280) (12,448) (24,946) (8,322)
Net income (loss) $ (8,404) $ 5,389 $ (20,122) $ (11,104) $ (23,549) $ (63,902) $ (36,606)
Net income (loss) per common share, basic:              
Basic net income (loss) per share, continuing operations (in dollars per share) $ (0.19) $ 0.91 $ (0.29) $ (0.13)      
Basic net loss per share, discontinued operations (in dollars per share) (0.03) (0.32) (0.34) (0.17)      
Basic net income (loss) per share (in dollars per share) $ (0.22) $ 0.59 $ (0.63) $ (0.30)      
Net loss per common share:              
Basic and diluted per share, continuing operations (usd per share)         $ (1.11) $ (5.02) $ (4.74)
Basic and diluted loss per share, discontinued operations (usd per share)         (1.25) (3.21) (1.39)
Basic and diluted net loss per share (usd per share)         $ (2.36) $ (8.23) $ (6.13)
Weighted-average common shares outstanding, basic (in shares) 37,421,273 9,101,730 31,944,243 9,035,173      
Weighted-average common shares outstanding: basic and diluted         9,958,802 7,763,236 5,969,418
Net income (loss) per common share, diluted:              
Diluted net income (loss) per share, continuing operations (in dollars per share) $ (0.19) $ 0.90 $ (0.29) $ (0.13)      
Diluted net loss per share, discontinued operations (in dollars per share) (0.03) (0.32) (0.34) (0.17)      
Diluted net income (loss) per share (in dollars per share) $ (0.22) $ 0.58 $ (0.63) $ (0.30)      
Weighted-average common shares outstanding, diluted (in shares) 37,421,273 9,273,867 31,944,243 9,035,173