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Legal Proceedings, Commitments and Contingencies - Summary of Litigation Settlements (Detail) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Loss Contingencies [Line Items]      
Total settlements $ 27,750    
Payable by the Company in cash 950    
Paid by the insurance carriers 21,700    
Paid by the Company in cash 2,450    
Paid by the Company in common stock 2,650 $ 1,000 $ 0
Galena Biopharma, Inc. Securities Litigation, Civil Action No. 3:14-cv-00367-SI      
Loss Contingencies [Line Items]      
Total settlements 20,000    
Galena Biopharma, Inc. Derivative Litigation, Civil Action No. 3:14-cv-00382-SI      
Loss Contingencies [Line Items]      
Total settlements 5,000    
Shareholders Securities Litigation      
Loss Contingencies [Line Items]      
Total settlements 1,800    
SEC Litigation      
Loss Contingencies [Line Items]      
Total settlements $ 950