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CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS EQUITY - USD ($)
$ in Thousands
Total
Settled Litigation
Senior Secured Debentures
Senior Notes [Member]
Common Stock
Common Stock
Settled Litigation
Additional Paid-In Capital
Additional Paid-In Capital
Settled Litigation
Additional Paid-In Capital
Senior Secured Debentures
Senior Notes [Member]
Accumulated Deficit
Treasury Stock
Treasury Stock
Settled Litigation
Treasury Stock
Senior Secured Debentures
Senior Notes [Member]
Beginning balance, shares at Dec. 31, 2013       5,505,035                
Beginning balance at Dec. 31, 2013 $ 5,886     $ 10   $ 188,600     $ (178,875) $ (3,849)    
Increase (Decrease) in Stockholders' Equity [Roll Forward]                        
Issuance of common stock, shares       331,650                
Issuance of common stock 10,705     $ 1   10,704            
Issuance of common stock under milestone achievement, shares       219,061                
Issuance of common stock under milestone achievement 9,340         9,340            
Issuance of common stock upon exercise of warrants, shares       273,351                
Issuance of common stock upon exercise of warrants 37,742     $ 1   37,741            
Issuance of common stock in connection with employee stock purchase plan, shares       5,732                
Issuance of common stock in connection with employee stock purchase plan 263         263            
Stock based compensation for directors and employees 5,253         5,253            
Stock based compensation for services 134         134            
Exercise of stock options, shares       172,488                
Exercise of stock options 4,342         4,342            
Net loss (36,606)               (36,606)      
Ending balance, shares at Dec. 31, 2014       6,507,317                
Ending balance at Dec. 31, 2014 37,059     $ 12   256,377     (215,481) (3,849)    
Increase (Decrease) in Stockholders' Equity [Roll Forward]                        
Issuance of common stock, shares       1,607,934                
Issuance of common stock 47,416     $ 3   47,413            
Common stock warrants issued (10,296)         (10,296)            
Issuance of common stock in connection with employee stock purchase plan, shares       11,566                
Issuance of common stock in connection with employee stock purchase plan 309         309            
Stock based compensation for directors and employees 2,896         2,896            
Exercise of stock options, shares       2,270                
Exercise of stock options 31         31            
Net loss (63,902)               (63,902)      
Ending balance, shares at Dec. 31, 2015       8,129,087                
Ending balance at Dec. 31, 2015 13,513     $ 15   296,730     (279,383) (3,849)    
Increase (Decrease) in Stockholders' Equity [Roll Forward]                        
Issuance of common stock, shares       2,872,803                
Stock Issued During Period, Shares, Other         206,903              
Issuance of common stock 33,534     $ 0   33,534            
Stock Issued During Period, Value, Other   $ 557     $ 0   $ 557       $ 0  
Common stock warrants issued (9,886)         (9,886)            
Stock issued during period to satisfy principal and interest on long-term debt, new shares       3,981,208                
Issuance of common stock to satisfy principal and interest of long-term debt 8,079     $ 0   8,079            
Common stock warrants issued in connection with debt financing     $ 1,139         $ 1,139       $ 0
Issuance of common stock upon exercise of warrants, shares       20,403                
Issuance of common stock upon exercise of warrants $ 95     $ 0   95            
Issuance of common stock in connection with employee stock purchase plan, shares 29,070     5,477                
Issuance of common stock in connection with employee stock purchase plan $ 2,650         2,650            
Stock based compensation for directors and employees $ 2,264         2,264            
Exercise of stock options, shares 8,000     8,342                
Exercise of stock options $ 261         261            
Net loss (23,549)               (23,549)      
Ending balance, shares at Dec. 31, 2016       15,224,223                
Ending balance (Scenario, Previously Reported [Member]) at Dec. 31, 2016       $ 15   335,423            
Ending balance at Dec. 31, 2016 28,657     $ 2   335,436     (302,932) (3,849)    
Increase (Decrease) in Stockholders' Equity [Roll Forward]                        
Stock Issued During Period, Shares, Other       17,000,000                
Stock Issued During Period, Value, Other 15,524     $ 2   15,522            
Common stock warrants issued (10,357)         (10,357)            
Issuance of common stock upon exercise of warrants, shares       5,150,660                
Issuance of common stock upon exercise of warrants 4,913         4,913            
Issuance of common stock in connection with employee stock purchase plan, shares       4,048                
Issuance of common stock in connection with employee stock purchase plan 5         5            
Stock based compensation for directors and employees $ 425         425            
Fair value of common stock in exchange for services, shares       90,343                
Exercise of stock options, shares 0                      
Fair value of common stock in exchange for services $ 82         82            
Net loss (20,122)               (20,122)      
Ending balance, shares at Jun. 30, 2017       37,469,274                
Ending balance at Jun. 30, 2017 $ 19,127     $ 4   $ 346,026     $ (323,054) $ (3,849)