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Warrants to Acquire Shares of Common Stock (Tables) | 9 Months Ended
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Sep. 30, 2018
Warrants and Rights Note Disclosure [Abstract] |
Schedule Of Warrant Activity Table | The following is a summary of the Company's warrants to acquire shares of common stock activity for the nine months ended September 30, 2018 (in thousands):
Warrant Issuance | Outstanding, December 31, 2017 |  | Granted |  | Exercised |  | Canceled/Expired |  | Outstanding, September 30, 2018 |  | Expiration
July 2018 Offering | — |  |  | 15,268 |  |  | — |  |  | — |  |  | 15,268 |  |  | July 2023
Pre-funded July 2018 Offering | — |  |  | 4,675 |  |  | (2,525 | ) |  | — |  |  | 2,150 |  |  | July 2023
Series A Convertible Preferred | — |  |  | 1,384 |  |  | — |  |  |  |  | 1,384 |  |  | September 2023
2017 Equilibria | 316 |  |  | — |  |  | — |  |  |  |  | 316 |  |  | December 2022
Galena February 2017 | 567 |  |  | — |  |  | — |  |  | (535 | ) |  | 32 |  |  | February 2022
Galena Other | 80 |  |  | — |  |  | — |  |  | (6 | ) |  | 74 |  |  | January 2022
| 963 |  |  | 21,327 |  |  | (2,525 | ) |  | (541 | ) |  | 19,224 |  |  |
Fair Value of Warrants is Estimated Using Black-Scholes Option Pricing Model | The fair value of the warrants is estimated using a Black-Scholes pricing model with the following inputs:
As of September 30, 2018
Warrant Issuance | Outstanding (in thousands) |  | Strike price (per share) |  | Expected term (years) |  | Volatility % |  | Risk-free rate %
Series A Convertible Preferred | 1,384 |  |  | $ | 2.10 |  |  | 5.01 |  | 83.18 | % |  | 2.94 | %
Galena February 2017 | 32 |  |  | $ | 33.00 |  |  | 3.38 |  | 85.39 | % |  | 2.25 | %
Galena Other | 74 |  |  | $ | 888.22 |  |  | 2.68 |  | 85.96 | % |  | 2.32 | %
As of December 31, 2017
Warrant Issuance | Outstanding (in thousands) |  | Strike price (per share) |  | Expected term (years) |  | Volatility % |  | Risk-free rate %
Galena February 2017 | 567 |  |  | $ | 13.00 |  |  | 4.12 |  | 79.29 | % |  | 2.09 | %
Galena Other | 80 |  |  | $ | 28.40 |  |  | 3.19 |  | 74.05 | % |  | 2.09 | %
Changes in Fair Value of Warrant Liability | The changes in fair value of the warrant liability for the nine months ended September 30, 2018 were as follows (in thousands):
Warrant Issuance | Warrant liability, December 31, 2017 |  | Fair value of warrants granted |  | Fair value of warrants canceled |  | Adjustment to exercise price of warrants |  | Change in fair value of warrants |  | Warrant liability, September 30, 2018
Series A Convertible Preferred | $ | — |  |  | $ | 5,039 |  |  | $ | — |  |  | $ | 491 |  |  | $ | (4,558 | ) |  | $ | 972 |
Galena February 2017 | 1,305 |  |  | — |  |  | (524 | ) |  | — |  |  | (778 | ) |  | 3 |
Galena Other | 4 |  |  | — |  |  | — |  |  | — |  |  | (4 | ) |  | — |
| $ | 1,309 |  |  | $ | 5,039 |  |  | $ | (524 | ) |  | $ | 491 |  |  | $ | (5,340 | ) |  | $ | 975 |

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