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Stock-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2018

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Schedule of Allocated Stock-based Compensation Expense

The following table summarizes the components of stock-based compensation expense in the condensed consolidated statements of operations for the three and nine months ended September 30, 2018 and 2017, respectively (in thousands):

	Three Months Ended September 30,								Nine Months Ended September 30,
	2018				2017				2018				2017
Research and development	$	21			$	543			$	55			$	729
General and administrative	115				724				229				3,047
Total stock-based compensation	$	136			$	1,267			$	284			$	3,776

Assumptions for Option Grants Issued

The Company uses the Black-Scholes option-pricing model and the following assumptions were used to determine the fair value of all its stock options granted during the nine months ended September 30, 2018:

	Nine Months Ended September 30, 2018
Risk free interest rate	2.73	%
Volatility	80.83	%
Expected lives (years)	6.20
Expected dividend yield	—	%

Stock Option Activity

The following table summarizes stock option activity of the Company for the nine months ended September 30, 2018:

	Total Number of Shares (In Thousands)			Weighted Average Exercise Price				Weighted Average Remaining Contractual Term (in years)		Aggregate Intrinsic Value (In Thousands)
Outstanding at January 1, 2018	10			$	1,240.55			1.00		$	—
Granted	483			5.24						—
Canceled	(59	)		5.24						$	—
Outstanding at September 30, 2018	434			$	34.17			9.26		$	—
Options exercisable at September 30, 2018	43			$	265.35			7.51		$	—

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Tabular disclosure of the allocation of equity-based compensation costs to a given line item on the balance sheet and income statement for the period. This may include the reporting line for the costs and the amount capitalized and expensed.

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Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

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