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Stock-Based Compensation (Allocated Stock-based Compensation) (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]        
Allocated share based compensation expense $ 136 $ 1,267 $ 284 $ 3,776
Research and development        
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]        
Allocated share based compensation expense 21 543 55 729
General and administrative        
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]        
Allocated share based compensation expense $ 115 $ 724 $ 229 $ 3,047