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Acquisition (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2018 | Dec. 31, 2017
Business Acquisition [Line Items] |  |
Business combination pro forma transaction costs |  | $ 8,700
Success fee and other transaction costs |  | $ 4,800
Stock issued for incentive fee payment in connection with acquisition during period shares |  | 119,672
Stock issued for incentive fee payment in connection with acquisition during period |  | $ 941
Severance costs | $ 0 | 1,883
Production related impairments or charges |  | 5,200
Galena Biopharma, Inc |  |
Business Acquisition [Line Items] |  |
Business combination pro forma transaction costs |  | $ 5,700

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