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Warrants to Acquire Shares of Common Stock - Schedule of Warrant Activity (Details) shares in Thousands | 12 Months Ended
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Dec. 31, 2018 shares
Class of Warrant or Right, Outstanding [Roll Forward] |
Warrants outstanding , Beginning balance (in shares) | 963
Granted (in shares) | 21,327
Exercised (in shares) | (4,050)
Canceled/Expired (in shares) | (542)
Warrants outstanding , Ending balance (in shares) | 17,698
July 2018 Offering |
Class of Warrant or Right, Outstanding [Roll Forward] |
Warrants outstanding , Beginning balance (in shares) | 0
Granted (in shares) | 15,268
Exercised (in shares) | 0
Canceled/Expired (in shares) | 0
Warrants outstanding , Ending balance (in shares) | 15,268
Pre-funded 2018 Offering |
Class of Warrant or Right, Outstanding [Roll Forward] |
Warrants outstanding , Beginning balance (in shares) | 0
Granted (in shares) | 4,675
Exercised (in shares) | (4,050)
Canceled/Expired (in shares) | 0
Warrants outstanding , Ending balance (in shares) | 625
Series A Convertible Preferred |
Class of Warrant or Right, Outstanding [Roll Forward] |
Warrants outstanding , Beginning balance (in shares) | 0
Granted (in shares) | 1,384
Exercised (in shares) | 0
Warrants outstanding , Ending balance (in shares) | 1,384
2017 Equilibria |
Class of Warrant or Right, Outstanding [Roll Forward] |
Warrants outstanding , Beginning balance (in shares) | 316
Granted (in shares) | 0
Exercised (in shares) | 0
Warrants outstanding , Ending balance (in shares) | 316
Galena February 2017 |
Class of Warrant or Right, Outstanding [Roll Forward] |
Warrants outstanding , Beginning balance (in shares) | 567
Granted (in shares) | 0
Exercised (in shares) | 0
Canceled/Expired (in shares) | (534)
Warrants outstanding , Ending balance (in shares) | 33
Galena Other |
Class of Warrant or Right, Outstanding [Roll Forward] |
Warrants outstanding , Beginning balance (in shares) | 80
Granted (in shares) | 0
Exercised (in shares) | 0
Canceled/Expired (in shares) | (8)
Warrants outstanding , Ending balance (in shares) | 72

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- Definition Number of warrants or rights outstanding. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 235 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.4-08.(i)) -URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e23780-122690 + Details
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