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CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY - USD ($) | Total | Preferred Stock | Common Stock | Additional Paid-In Capital | Accumulated Deficit | Patel vs Galena biopharma, Inc | Patel vs Galena biopharma, Inc Common Stock | Patel vs Galena biopharma, Inc Additional Paid-In Capital | Secured Debt | Secured Debt Common Stock | Secured Debt Additional Paid-In Capital | Convertible Preferred Stock | Convertible Preferred Stock Preferred Stock | Convertible Preferred Stock Common Stock | Convertible Preferred Stock Additional Paid-In Capital | Convertible Notes Payable | Convertible Notes Payable Common Stock | Convertible Notes Payable Additional Paid-In Capital
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Beginning balance (in shares) at Dec. 31, 2016 |  | 0 | 1,268,489 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Beginning balance at Dec. 31, 2016 | $ (4,997,000) | $ 0 | $ 0 | $ 25,434,000 | $ (30,431,000) |  |  |  |  |  |  |  |  |  |  |  |  |
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock issued in connection with amendments to MSK license, shares |  |  | 83,594 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock issued in connection with amendments to MSK license, amount | 388,000 |  |  | 388,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock (in shares) |  |  | 330,551 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock as result of conversion | 1,294,000 |  |  | 1,294,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of stock (in shares) |  |  | 1,534,711 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of stock, amount | 6,007,000 |  |  | 6,007,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued in connection with settlement of related party payables, shares |  |  | 96,662 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued in connection with settlement of related party payables, amount | 378,000 |  |  | 378,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued upon the acceleration of restricted stock units, shares |  |  | 46,373 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued upon cancellation of Equilibria restricted stock units, shares |  |  | 58,208 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued in connection with acquisition of Galena, shares |  |  | 1,588,605 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued in connection with acquisition of Galena | 12,487,000 |  | $ 1,000 | 12,486,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair value of assumed options issued in connection with acquisition of Galena | 32,000 |  |  | 32,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares and common stock warrants issued upon conversion of 2015 Sely Note and accrued interest to Equilibria, shares |  |  | 632,326 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares and common stock warrants issued upon conversion of 2015 Sely Note and accrued interest to Equilibria, value | 6,739,000 |  |  | 6,739,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deemed dividend associated with conversion of 2015 Sely Note and common stock warrant issuance to Equilibria | $ (675,000) |  |  | (675,000) |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued to Equilibria for incentive fee payment in connection with the acquisition of Galena, shares | 119,672 |  | 119,672 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued to Equilibria for incentive fee payment in connection with the acquisition of Galena | $ 941,000 |  |  | 941,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued to MSK for anti-dilution provisions, shares |  |  | 7,700 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued to MSK for anti-dilution provisions | 61,000 |  |  | 61,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock-based compensation expense | 3,169,000 |  |  | 3,169,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deemed dividend arising from the issuance of common stock to Series A convertible preferred stockholders under most favored nation provision | 0 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Net loss | (23,754,000) |  |  |  | (23,754) |  |  |  |  |  |  |  |  |  |  |  |  |
Ending balance (in shares) at Dec. 31, 2017 |  | 0 | 5,766,891 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Ending balance at Dec. 31, 2017 | 2,070,000 | $ 0 | $ 1,000 | 56,254,000 | (54,185,000) |  |  |  |  |  |  |  |  |  |  |  |  |
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock (in shares) |  | (2,898) | 499,682 |  |  |  |  |  |  |  |  |  | (7,802) | 3,748,184 |  |  | 118,644 |
Issuance of common stock as result of conversion |  |  |  |  |  |  |  |  |  |  |  | $ (8,654,000) |  |  | $ (8,654,000) | $ 825,000 |  | $ 825,000
Issuance of stock (in shares) |  | 10,700 | 6,845,000 |  |  |  | 228,672 |  |  | 715,277 |  |  |  |  |  |  |  |
Issuance of stock, amount | 21,564,000 |  | $ 1,000 | 21,563,000 |  | $ 1,250,000 |  | $ 1,250,000 | $ 2,896,000 |  | $ 2,896,000 |  |  |  |  |  |  |
Issuance of Series A convertible preferred stock, net of offering costs | 9,647,000 |  |  | 9,647,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair value of liability-classified warrants issued in connection with Series A convertible preferred stock offering | (5,039,000) |  |  | (5,039,000) |  |  |  |  |  |  |  |  |  |  |  |  |  |
Beneficial conversion feature arising from Series A convertible preferred stock | (4,436,000) |  |  | (4,436,000) |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deemed dividend arising from beneficial conversion feature of Series A convertible preferred stock | 4,436,000 |  |  | 4,436,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deemed dividend arising from the issuance of common stock to Series A convertible preferred stockholders under most favored nation provision | 8,654,000 |  |  | 8,654,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Impact of anti-dilution protection on liability-classified warrants | (491,000) |  |  | (491,000) |  |  |  |  |  |  |  |  |  |  |  |  |  |
Convertible preferred stock dividends | (487,000) |  |  | (487,000) |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock in connection with warrant exchange agreements (in shares) |  |  | 54,343 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock in connection with warrant exchange agreements | 285,000 |  |  | 285,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock upon exercise of pre-funded warrants |  |  | 4,049,783 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock-based compensation | 395,000 |  |  | 395,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Net loss | (27,670,000) |  |  |  | (27,670,000) |  |  |  |  |  |  |  |  |  |  |  |  |
Ending balance (in shares) at Dec. 31, 2018 |  | 0 | 22,026,476 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Ending balance at Dec. 31, 2018 | $ 5,245,000 | $ 0 | $ 2,000 | $ 87,098,000 | $ (81,855,000) |  |  |  |  |  |  |  |  |  |  |  |  |

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