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Warrants to Acquire Shares of Common Stock - Narrative (Details)
 1 Months Ended 12 Months Ended
Apr. 30, 2018
USD ($)
shares
Dec. 31, 2018
USD ($)
$ / shares
shares
Dec. 31, 2017
USD ($)
Jul. 16, 2018
$ / shares
May 31, 2018
$ / shares
Dec. 29, 2017
$ / shares
Class of Warrant or Right [Line Items]            
Shares issued for cancellation of warrants (in shares)   54,613        
Surrender and cancellation of warrants (in shares)   121,667        
Common stock acquired in exchange for warrants (in shares)   412,667        
Fair value of consideration exchanged | $   $ 1,200,000        
Loss On Settlement Of Warrants Liability | $   $ 727,000 $ 0      
Exercise price (usd per share) | $ / shares       $ 2.10 $ 6.59 $ 7.42
Galena February 2017            
Class of Warrant or Right [Line Items]            
Class of warrant or right canceled   534,334        
Series A Convertible Preferred            
Class of Warrant or Right [Line Items]            
Exercise price (usd per share) | $ / shares   $ 6.59        
Convertible Promissory Notes | Convertible Notes Payable            
Class of Warrant or Right [Line Items]            
Debt instrument, face amount | $   $ 1,000,000.0        
Common stock acquired in exchange for warrants (in shares)   412,667        
Warrants and rights outstanding | $ $ 800,000          
Conversion of units (in shares) 118,644          
Measurement Input, Price Volatility            
Class of Warrant or Right [Line Items]            
Warrants and rights outstanding, measurement input           0.9010
Measurement Input, Risk Free Interest Rate            
Class of Warrant or Right [Line Items]            
Warrants and rights outstanding, measurement input   0       0.0220
Measurement Input, Expected Dividend Rate            
Class of Warrant or Right [Line Items]            
Warrants and rights outstanding, measurement input   0       0