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Warrants to Acquire Shares of Common Stock - Changes in Fair Value of Warrant Liability (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2018 USD ($)
Class of Warrant or Right, Fair Value [Roll Forward]
Warrant liability, Beginning balance	$ 1,309
Fair value of warrants granted	5,039
Fair value of warrants canceled	(526)
Adjustment to exercise price of warrants	491
Change in fair value of warrants	(5,300)
Warrant liability, Ending balance	1,013
Series A Convertible Preferred
Class of Warrant or Right, Fair Value [Roll Forward]
Warrant liability, Beginning balance	0
Fair value of warrants granted	5,039
Fair value of warrants canceled	0
Adjustment to exercise price of warrants	491
Change in fair value of warrants	(4,520)
Warrant liability, Ending balance	1,010
Galena February 2017
Class of Warrant or Right, Fair Value [Roll Forward]
Warrant liability, Beginning balance	1,305
Fair value of warrants granted	0
Fair value of warrants canceled	(526)
Adjustment to exercise price of warrants	0
Change in fair value of warrants	(776)
Warrant liability, Ending balance	3
Galena Other
Class of Warrant or Right, Fair Value [Roll Forward]
Warrant liability, Beginning balance	4
Fair value of warrants granted	0
Fair value of warrants canceled	0
Adjustment to exercise price of warrants	0
Change in fair value of warrants	(4)
Warrant liability, Ending balance	$ 0