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License Revenue with 3D Medicines, Inc. - Narrative (Details) - USD ($)
 1 Months Ended 12 Months Ended
Dec. 31, 2020
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Revenue from Contract with Customer [Abstract]        
Upfront cash payment received $ 7,500,000 $ 7,500,000    
Future milestone payments received $ 194,500,000      
Royalties payable, maximum term 15 years      
Royalties payable, minimum term 10 years      
Termination threshold 2 years      
Performance obligation, amount   9,500,000    
Milestones probable of being achieved   2,000,000    
Milestone payment received   2,000,000    
Potential milestone payments to be received   192,500,000    
Licensing revenue   7,600,000 $ 1,900,000  
Deferred revenue $ 5,600,000 0 5,600,000 $ 0
Contract acquisition costs   1,400,000    
Amortization of contract asset   1,100,000 300,000  
Cost of revenue   $ 200,000 $ 0