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Major Customers, Partnerships and Strategic Alliances (Tables)

9 Months Ended

Sep. 30, 2012

Shire AG [Member]

Research and Development Arrangement, Contract to Perform for Others [Line Items]

Revenues recognized under the agreement

		Three months ended September 30,								Nine months ended September 30,
		2012				2011				2012				2011
Revenue related to Sigma Collaboration:
Royalty revenues		$	428			$	161			$	1,035			$	591
License fee and milestone revenues			—				—				1,000				671
Total			428				161				2,035				1,262

Sigma-Aldrich Corporation [Member]

Research and Development Arrangement, Contract to Perform for Others [Line Items]

Revenues recognized under the agreement

		Three months ended September 30, 2012				Nine months ended September 30, 2012
Revenue related to Shire Collaboration:
Amortization of upfront fee		$	542			$	1,444
Research services			2,675				4,747
Total		$	3,217			$	6,191

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- Definition

Tabular disclosure of patient service revenue (net of contractual allowances and discounts), by major payor source of revenue for health care organizations.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 954

-SubTopic 605

-Section 50

-Paragraph 4

-Subparagraph (b)

-URI http://asc.fasb.org/extlink&oid=9156300&loc=SL9156464-115641



Reference 2: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 954

-SubTopic 605

-Section 55

-Paragraph 4

-URI http://asc.fasb.org/extlink&oid=9156477&loc=SL9156489-173031

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