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Condensed Consolidated Statements of Comprehensive Loss (Unaudited) (USD $)
In Thousands, except Per Share data, unless otherwise specified
3 Months Ended 9 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Revenues:        
Collaboration agreements $ 4,190 $ 781 $ 9,665 $ 2,876
Research grants 717 1,076 3,058 2,695
Total revenues 4,907 1,857 12,723 5,571
Operating expenses:        
Research and development 7,570 7,839 22,427 24,220
General and administrative 3,139 3,592 9,125 10,807
Total operating expenses 10,709 11,431 31,552 35,027
Loss from operations (5,802) (9,574) (18,829) (29,456)
Interest income, net 12 20 43 65
Net loss (5,790) (9,554) (18,786) (29,391)
Basic and diluted net loss per share $ (0.11) $ (0.18) $ (0.36) $ (0.59)
Shares used in computing basic and diluted net loss per share 52,768 52,464 52,664 49,850
Net loss (5,790) (9,554) (18,786) (29,391)
Changes in unrealized gain (loss) on available-for-sale securities 22 (19) 3 4
Comprehensive loss $ (5,768) $ (9,573) $ (18,783) $ (29,387)