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Property and Equipment (Details) (USD $)
In Thousands, unless otherwise specified
Dec. 31, 2012
Dec. 31, 2011
Summary of property and equipment    
Property and equipment, Gross $ 4,495 $ 4,329
Less accumulated depreciation (2,952) (2,726)
Property and equipment, net 1,543 1,603
Laboratory equipment [Member]
   
Summary of property and equipment    
Property and equipment, Gross 2,950 2,851
Furniture and Fixtures [Member]
   
Summary of property and equipment    
Property and equipment, Gross 499 442
Leasehold Improvements [Member]
   
Summary of property and equipment    
Property and equipment, Gross $ 1,046 $ 1,036