XML 53 R4.htm IDEA: XBRL DOCUMENT v2.4.0.6
Consolidated Statements of Operations (USD $)
In Thousands, except Per Share data, unless otherwise specified
 12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Revenues:      
Collaboration agreements $ 18,186 $ 6,110 $ 16,819
Research grants 3,469 4,209 3,986
Total revenues 21,655 10,319 20,805
Operating expenses:      
Research and development 31,709 32,098 33,154
General and administrative 12,144 14,042 12,586
Total operating expenses 43,853 46,140 45,740
Loss from operations (22,198) (35,821) (24,935)
Other income (expense), net (66) 71 81
Net loss $ (22,264) $ (35,750) $ (24,854)
Basic and diluted net loss per share $ (0.42) $ (0.71) $ (0.55)
Shares used in computing basic and diluted net loss per share 52,741 50,512 45,167