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Major Customers, Partnerships and Strategic Alliances - Revenues Recognized under Agreement (Detail) (USD $) In Thousands, unless otherwise specified | 1 Months Ended | 3 Months Ended | 9 Months Ended
--- | --- | --- | ---
Apr. 30, 2013 | Sep. 30, 2013 | Sep. 30, 2012 | Sep. 30, 2013 | Sep. 30, 2012
Shire AG [Member] |  |  |  |  |
Revenue related to Shire Collaboration: |  |  |  |  |
Amortization of upfront fee |  | $ 542 | $ 542 | $ 1,625 | $ 1,444
Research services |  | 3,968 | 2,675 | 11,340 | 4,747
Total |  | 4,510 | 3,217 | 12,965 | 6,191
Revenue related to Sigma Collaboration: |  |  |  |  |
Royalty revenues |  |  |  | 0 |
Sigma-Aldrich Corporation [Member] |  |  |  |  |
Revenue related to Sigma Collaboration: |  |  |  |  |
Royalty revenues |  | 201 | 428 | 711 | 1,035
License fee and milestone revenues | 1,300 | 101 |  | 1,351 | 1,000
Total |  | $ 302 | $ 428 | $ 2,062 | $ 2,035

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- Definition Amount of revenue, fees and commissions earned from transactions between (a) a parent company and its subsidiaries; (b) subsidiaries of a common parent; (c) an entity and trusts for the benefit of employees, for example, but not limited to, pension and profit-sharing trusts that are managed by or under the trusteeship of the entity's management; (d) an entity and its principal, owners, management, or members of their immediate families; and (e) affiliates. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.1(e)) -URI http://asc.fasb.org/extlink&oid=26872669&loc=d3e20235-122688 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 03 -Paragraph 1 -Article 5 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Related Parties -URI http://asc.fasb.org/extlink&oid=16382449 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 946 -SubTopic 225 -Section S99 -Paragraph 1 -Subparagraph (SX 210.6-07.1(c)) -URI http://asc.fasb.org/extlink&oid=6488393&loc=d3e606610-122999 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 07 -Paragraph b -Subparagraph 1 -Article 6 + Details
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