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Major Customers, Partnerships and Strategic Alliances (Tables)
9 Months Ended
Sep. 30, 2013
Sigma-Aldrich Corporation [Member]
 
Revenues Recognized under Agreement

Revenues recognized under the agreement with Sigma for the three and nine months ended September 30, 2013 and September 30, 2012, were as follows (in thousands):

 

     Three months ended
September 30,
     Nine months ended
September 30,
 
     2013      2012      2013      2012  

Revenue related to Sigma Collaboration:

           

Royalty revenues

   $ 201       $ 428       $ 711       $ 1,035   

License fee and milestone revenues

     101         —           1,351         1,000   
  

 

 

    

 

 

    

 

 

    

 

 

 

Total

   $ 302       $ 428       $ 2,062       $ 2,035   
  

 

 

    

 

 

    

 

 

    

 

 

 
Shire AG [Member]
 
Revenues Recognized under Agreement

Revenues recognized under the agreement with Shire for the three and nine months ended September 30, 2013 and September 30, 2012, were as follows (in thousands):

 

     Three months ended
September 30,
     Nine months ended
September 30,
 
     2013      2012      2013      2012  

Revenue related to Shire Collaboration:

           

Amortization of upfront fee

   $ 542       $ 542       $ 1,625       $ 1,444   

Research services

     3,968         2,675         11,340         4,747   
  

 

 

    

 

 

    

 

 

    

 

 

 

Total

   $ 4,510       $ 3,217       $ 12,965       $ 6,191