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Acquisition of Ceregene - Schedule of Supplemental Pro Forma Information (Detail) (Ceregene, Inc. [Member], USD $) In Thousands, except Per Share data, unless otherwise specified | 12 Months Ended
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Dec. 31, 2013 | Dec. 31, 2012
Ceregene, Inc. [Member] |  |
Business Acquisition Pro Forma Information [Line Items] |  |
Net loss | $ (30,997) | $ (27,446)
Basic net loss per share | $ (0.55) | $ (0.52)

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