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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2013
Income Tax Disclosure [Abstract]  
Schedule of Company's Deferred Tax Assets

Significant components of the Company’s deferred tax assets are as follows (in thousands):

 

     December 31,  
     2013     2012  

Assets:

    

Deferred tax assets:

    

Net operating loss carryforwards

   $ 81,944      $ 73,129   

Research and development tax credit carryforwards

     7,996        6,770   

Capitalized research

     —          5   

Stock-based compensation

     7,927        7,375   

Deferred Revenue

     3,563        —     

Other

     1,677        937   
  

 

 

   

 

 

 

Total deferred tax asset

     103,107        88,216   

Valuation allowance

     (103,107 )     (88,216 )
  

 

 

   

 

 

 

Net deferred tax assets

   $ —        $ —     
  

 

 

   

 

 

 

Liabilities:

    

Net deferred tax liability related to intangible assets

     (748 )     —     
  

 

 

   

 

 

 

Total deferred tax liability

   $ (748 )   $ —     
  

 

 

   

 

 

Summary of Activity Related to Company's Unrecognized Tax Benefits

The following table summarizes the activity related to the Company’s unrecognized tax benefits (in thousands):

 

     December 31,  
     2013      2012     2011  

Beginning balance

   $ 2,735       $ 2,750      $ 1,896   

Additions based on tax positions related to the current year

     294         153        589   

Additions for tax positions of prior years

     153         58        265   

Reductions for tax positions of prior years

     —           (227 )     —     
  

 

 

    

 

 

   

 

 

 

Ending balance

   $ 3,182       $ 2,734      $ 2,750