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Consolidated Statements of Operations (USD $)
In Thousands, except Per Share data, unless otherwise specified
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Revenues:      
Collaboration agreements $ 21,678 $ 18,186 $ 6,110
Research grants 2,455 3,469 4,209
Total revenues 24,133 21,655 10,319
Operating expenses:      
Research and development 36,979 31,709 32,098
General and administrative 13,800 12,144 14,042
Change in fair value of contingent liability 60    
Total operating expenses 50,839 43,853 46,140
Loss from operations (26,706) (22,198) (35,821)
Other income (expense), net 82 (66) 71
Net loss $ (26,624) $ (22,264) $ (35,750)
Basic and diluted net loss per share $ (0.48) $ (0.42) $ (0.71)
Shares used in computing basic and diluted net loss per share 55,974 52,741 50,512