Major Customers, Partnerships and Strategic Alliances (Tables)

6 Months Ended

Jun. 30, 2014

Shire AG [Member]

Revenues recognized under the agreement with Shire for the three and six months ended June 30, 2014 and 2013, were as follows (in thousands):


	Three months ended June 30,				Six months ended June 30,
	2014		2013		2014		2013
Revenue related to Shire Collaboration:
Recognition of upfront fee	$	542	$	542	$	1,083	$	1,083
Research services		5,930		4,157		10,910		7,372

Total	$	6,472	$	4,699	$	11,993	$	8,455

Sigma-Aldrich Corporation [Member]

Revenues recognized under the agreement with Sigma for the three and six months ended June 30, 2014 and 2013, were as follows (in thousands):


	Three months ended June 30,				Six months ended June 30,
	2014		2013		2014		2013
Revenue related to Sigma Collaboration:
Royalty revenues	$	97	$	196	$	203	$	510
License fee and milestone revenues		—		1,250		179		1,250

Total	$	97	$	1,446	$	382	$	1,760

Biogen [Member]

Revenues recognized under the agreement with Biogen for the three and six months ended June 30, 2014 are as follows (in thousands):


	Three months ended June 30 ,		Six months ended June 30 ,
	2014		2014
Revenue related to Biogen Collaboration:
Recognition of upfront fee	$	1,540	$	2,200
Research services		1,338		1,761

Total	$	2,878	$	3,961