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Condensed Consolidated Statements of Operations (USD $)
In Thousands, except Per Share data, unless otherwise specified
 3 Months Ended 6 Months Ended
Jun. 30, 2014
Jun. 30, 2013
Jun. 30, 2014
Jun. 30, 2013
Revenues:        
Collaboration agreements $ 9,721 $ 6,157 $ 17,289 $ 10,240
Research grants 664 777 1,212 1,317
Total revenues 10,385 6,934 18,501 11,557
Operating expenses:        
Research and development 13,430 9,278 25,463 17,498
General and administrative 3,972 3,124 7,616 6,432
Change in fair value of contingent liability 30   80  
Total operating expenses 17,432 12,402 33,159 23,930
Loss from operations (7,047) (5,468) (14,658) (12,373)
Interest and other income, net 66 18 105 38
Net loss $ (6,981) $ (5,450) $ (14,553) $ (12,335)
Basic and diluted net loss per share $ (0.10) $ (0.10) $ (0.22) $ (0.23)
Shares used in computing basic and diluted net loss per share 67,980 53,786 65,603 53,583