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Stock-Based Compensation - Additional Information (Detail) (USD $)
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Total compensation cost related to unvested stock options and RSU $ 17,200,000us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions    
Weighted-average period of unvested stock options and RSU 3 years 15 days    
Capitalized stock-based employee compensation expense 0us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsCapitalizedAmount    
Weighted-average estimated fair value per share of options granted $ 8.16us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue $ 8.29us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue $ 3.76us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
Issuance of common stock under employee stock purchase plan, shares 107,203us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans 180,551us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans 175,375us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans
Stock issued under employee stock purchase plans, average exercise price $ 7.92sgmo_StockIssuedUnderEmployeeStockPurchasePlansAverageExercisePrice $ 2.75sgmo_StockIssuedUnderEmployeeStockPurchasePlansAverageExercisePrice $ 2.61sgmo_StockIssuedUnderEmployeeStockPurchasePlansAverageExercisePrice
Weighted-average estimated fair value of shares purchased under ESPP plan $ 3.25sgmo_EmployeeStockPurchasePlanRightsWeightedAverageEstimatedFairValue $ 1.47sgmo_EmployeeStockPurchasePlanRightsWeightedAverageEstimatedFairValue $ 2.51sgmo_EmployeeStockPurchasePlanRightsWeightedAverageEstimatedFairValue
Restricted Stock Units (RSUs) [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Total compensation cost related to unvested stock options and RSU $ 8,500,000us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions
/ us-gaap_AwardTypeAxis
= us-gaap_RestrictedStockUnitsRSUMember
   
Weighted-average period of unvested stock options and RSU 2 years 3 months 18 days