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Condensed Consolidated Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
3 Months Ended
Mar. 31, 2015
Mar. 31, 2014
Operating Activities:    
Net loss $ (5,319)us-gaap_NetIncomeLoss $ (7,572)us-gaap_NetIncomeLoss
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 147us-gaap_DepreciationDepletionAndAmortization 123us-gaap_DepreciationDepletionAndAmortization
Amortization of premium on marketable securities 241us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments 295us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments
Stock-based compensation 2,953us-gaap_ShareBasedCompensation 1,907us-gaap_ShareBasedCompensation
Change in fair value of contingent consideration liability (1,800)us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1 50us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1
Intangible impairment 1,870us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill  
Benefit from income taxes (748)us-gaap_DeferredIncomeTaxExpenseBenefit  
Net changes in operating assets and liabilities:    
Interest receivable 25us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet (45)us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet
Accounts receivable 3,730us-gaap_IncreaseDecreaseInAccountsReceivable (2,205)us-gaap_IncreaseDecreaseInAccountsReceivable
Prepaid expenses and other assets 101us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets (71)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Accounts payable and accrued liabilities (2,477)us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities 1,732us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
Accrued compensation and employee benefits (1,150)us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities (1,723)us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities
Deferred revenues 34us-gaap_IncreaseDecreaseInDeferredRevenue 18,888us-gaap_IncreaseDecreaseInDeferredRevenue
Net cash provided by / (used in) operating activities (2,393)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations 11,379us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
Investing Activities:    
Purchases of marketable securities (39,423)us-gaap_PaymentsToAcquireMarketableSecurities (16,773)us-gaap_PaymentsToAcquireMarketableSecurities
Maturities of marketable securities 58,955us-gaap_ProceedsFromSaleAndMaturityOfMarketableSecurities 20,786us-gaap_ProceedsFromSaleAndMaturityOfMarketableSecurities
Purchases of property and equipment (1,084)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment (126)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Net cash provided by investing activities 18,448us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations 3,887us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
Financing Activities:    
Proceeds from public offering of common stock, net of issuance costs   93,786sgmo_NetProceedsFromIssuancePublicOffering
Taxes paid related to net share settlement of equity awards (7)us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation  
Proceeds from issuance of common stock 3,178us-gaap_ProceedsFromIssuanceOfCommonStock 7,585us-gaap_ProceedsFromIssuanceOfCommonStock
Net cash provided by financing activities 3,171us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations 101,371us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
Net increase in cash and cash equivalents 19,226us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease 116,637us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease
Cash and cash equivalents, beginning of period 6,030us-gaap_CashAndCashEquivalentsAtCarryingValue 10,186us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents, end of period 25,256us-gaap_CashAndCashEquivalentsAtCarryingValue 126,823us-gaap_CashAndCashEquivalentsAtCarryingValue
Supplemental disclosure of noncash investing activities:    
Property, plant and equipment included in accrued liabilities $ 579us-gaap_CapitalExpendituresIncurredButNotYetPaid