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Major Customers, Partnerships and Strategic Alliances - Revenues Recognized under Agreement (Detail) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2015	Jun. 30, 2014	Jun. 30, 2015	Jun. 30, 2014
Biogen Inc [Member]
Revenues:
Recognition of upfront fee	$ 1,540,000	$ 1,540,000	$ 3,063,000	$ 2,200,000
Royalty revenues			0
Research services	1,701,000	1,338,000	3,233,000	1,761,000
Total	3,241,000	2,878,000	6,296,000	3,961,000
Shire AG [Member]
Revenues:
Recognition of upfront fee	542,000	542,000	1,083,000
Royalty revenues			0
Research services	3,894,000	5,930,000	10,910,000
Total	4,436,000	6,472,000	11,993,000
Sigma-Aldrich Corporation [Member]
Revenues:
Recognition of upfront fee			5,000,000
Royalty revenues	28,000	97,000	293,000	203,000
License fee revenues	21,000		4,277,000	179,000
Total	$ 49,000	$ 97,000	$ 4,570,000	$ 382,000

X

- Definition

Research service revenue under collaboration agreement.

+ References

No definition available.

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- Definition

Revenue earned during the period arising from products sold or services provided under the terms of a contract, not elsewhere specified in the taxonomy. May include government contracts, construction contracts, and any other contract related to a particular project or product.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef



-Publisher FASB



-Name Accounting Standards Codification



-Topic 225



-SubTopic 10



-Section S99



-Paragraph 2



-Subparagraph (SX 210.5-03.1)



-URI http://asc.fasb.org/extlink&oid=26872669&loc=d3e20235-122688

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- Definition

Revenue from multiple-deliverable arrangements that include licensing fees and services revenue. Licensing revenue is consideration received from another party for the right to use, but not own, certain of the entity's intangible assets. Licensing arrangements include, but are not limited to, rights to use a patent, copyright, technology, manufacturing process, software or trademark. Licensing fees are generally, but not always, fixed as to amount and not dependent upon the revenue generated by the licensing party. An entity may receive licensing fees for licenses that also generate royalty payments to the entity. Services revenue may be derived by providing other, nonspecified, services during the reporting period.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef



-Publisher FASB



-Name Accounting Standards Codification



-Topic 225



-SubTopic 10



-Section S99



-Paragraph 2



-Subparagraph (SX 210.5-03.1(d),(e))



-URI http://asc.fasb.org/extlink&oid=26872669&loc=d3e20235-122688



Reference 2: http://www.xbrl.org/2003/role/presentationRef



-Publisher SEC



-Name Regulation S-X (SX)



-Number 210



-Section 03



-Paragraph 1



-Article 5

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- Definition

Revenue earned during the period relating to consideration received from another party for the right to use, but not own, certain of the entity's intangible assets. Licensing arrangements include, but are not limited to, rights to use a patent, copyright, technology, manufacturing process, software or trademark. Licensing fees are generally, but not always, fixed as to amount and not dependent upon the revenue generated by the licensing party. An entity may receive licensing fees for licenses that also generate royalty payments to the entity.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef



-Publisher FASB



-Name Accounting Standards Codification



-Topic 225



-SubTopic 10



-Section S99



-Paragraph 2



-Subparagraph (SX 210.5-03.1(e))



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- Definition

Revenue earned during the period from the leasing or otherwise lending to a third party the entity's rights or title to certain property. Royalty revenue is derived from a percentage or stated amount of sales proceeds or revenue generated by the third party using the entity's property. Examples of property from which royalties may be derived include patents and oil and mineral rights.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef



-Publisher FASB



-Name Accounting Standards Codification



-Topic 225



-SubTopic 10



-Section S99



-Paragraph 2



-Subparagraph (SX 210.5-03.1(e))



-URI http://asc.fasb.org/extlink&oid=26872669&loc=d3e20235-122688



Reference 2: http://www.xbrl.org/2003/role/presentationRef



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-Name Regulation S-X (SX)



-Number 210



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-Paragraph 1



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