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Major Customers, Partnerships and Strategic Alliances (Tables)

9 Months Ended

Sep. 30, 2015

Biogen Inc [Member]

Research and Development Arrangement, Contract to Perform for Others [Line Items]

Revenues Recognized under Agreement

Revenues recognized under the agreement with Biogen for the three and nine months ended September 30, 2015 and 2014 are as follows (in thousands):

		Three months ended								Nine months ended
		September 30,								September 30,
		2015				2014				2015				2014
Revenue related to Biogen Collaboration:
Recognition of upfront fee		$	1,556			$	1,557			$	4,619			$	3,756
Research services			2,594				3,508				5,827				5,270
Total		$	4,150			$	5,065			$	10,446			$	9,026

Shire AG [Member]

Research and Development Arrangement, Contract to Perform for Others [Line Items]

Revenues Recognized under Agreement

Revenues recognized under the agreement with Shire for the three and nine months ended September 30, 2015 and 2014, were as follows (in thousands):

		Three months ended								Nine months ended
		September 30,								September 30,
		2015				2014				2015				2014
Revenue related to Shire Collaboration:
Recognition of upfront fee		$	542			$	542			$	1,625			$	1,625
Recognition of milestone			—				1,000				—				1,000
Research services			3,313				5,002				11,729				15,912
Total		$	3,855			$	6,544			$	13,354			$	18,537

Sigma-Aldrich Corporation [Member]

Research and Development Arrangement, Contract to Perform for Others [Line Items]

Revenues Recognized under Agreement

Revenues recognized under the agreement with Sigma for the three and nine months ended September 30, 2015 and 2014, were as follows (in thousands):

		Three months ended								Nine months ended
		September 30,								September 30,
		2015				2014				2015				2014
Revenue related to Sigma Collaboration:
Royalty revenues		$	97			$	67			$	390			$	270
License fee revenues			172				269				4,449				447
Total		$	269			$	336			$	4,839			$	717

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

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- Definition

Tabular disclosure of contractual arrangements that involve two or more parties that both: (i) actively participate in a joint operating activity and (ii) are exposed to significant risks and rewards that depend on the commercial success of the joint operating activity. Additionally, the element may include all other transactions of the entity categorized collectively, if such comparison of collaborative arrangements as a component of all transactions of the entity is desired.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef



-Publisher FASB



-Name Accounting Standards Codification



-Topic 808



-SubTopic 10



-Section 50



-Paragraph 1



-URI http://asc.fasb.org/extlink&oid=6931272&loc=SL5834143-161434

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