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Major Customers, Partnerships and Strategic Alliances - California Institute for Regenerative Medicine - Additional Information (Detail) - USD ($) $ in Thousands	1 Months Ended		3 Months Ended		9 Months Ended
	May. 31, 2014	May. 31, 2013	Sep. 30, 2015	Sep. 30, 2014	Sep. 30, 2015	Sep. 30, 2014
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Research grants			$ 163	$ 372	$ 1,540	$ 1,584
California Institute for Regenerative Medicine [Member]
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Funds due under the agreement	$ 5,600
Agreement to receive	4 years
Research grants			0	0	0	0
Collaboration agreement related costs and expenses			600	0	1,300	0
California Institute for Regenerative Medicine [Member] \| Beta-thalassemia [Member]
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Funds due under the agreement		$ 6,400
Agreement to receive		4 years
Research grants			0	400	1,200	1,100
Collaboration agreement related costs and expenses			0	$ 400	$ 1,200	$ 1,100
Unused funds received			$ 3,000