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Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2015	Sep. 30, 2014	Sep. 30, 2015	Sep. 30, 2014
Revenues:
Collaboration agreements	$ 8,406	$ 12,045	$ 28,878	$ 29,334
Research grants	163	372	1,540	1,584
Total revenues	8,569	12,417	30,418	30,918
Operating expenses:
Research and development	16,694	16,340	47,292	41,883
General and administrative	4,560	3,731	14,309	11,347
Total operating expenses	21,254	20,071	61,601	53,230
Loss from operations	(12,685)	(7,654)	(31,183)	(22,312)
Interest and other income, net	101	109	406	214
Loss before income taxes	(12,584)	(7,545)	(30,777)	(22,098)
Benefit from income taxes	3,339		4,087
Net loss	$ (9,245)	$ (7,545)	$ (26,690)	$ (22,098)
Basic and diluted net loss per share	$ (0.13)	$ (0.11)	$ (0.38)	$ (0.33)
Shares used in computing basic and diluted net loss per share	69,892	68,230	69,622	66,488

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