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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Operating Activities:    
Net loss $ (26,690) $ (22,098)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 745 400
Amortization of premium on marketable securities 681 843
Stock-based compensation 8,664 6,165
Change in fair value of contingent consideration liability (1,800) 130
Intangible impairment 1,870  
Benefit from income taxes (4,087)  
Net changes in operating assets and liabilities:    
Interest receivable 24 25
Accounts receivable 3,364 (5,319)
Prepaid expenses and other assets 129 (1,059)
Accounts payable and accrued liabilities (2,534) 3,619
Accrued compensation and employee benefits (74) (530)
Deferred revenues (4,908) 14,861
Net cash used in operating activities (24,616) (2,963)
Investing Activities:    
Purchases of marketable securities (168,627) (176,385)
Maturities of marketable securities 203,175 76,605
Purchases of property and equipment (2,327) (559)
Net cash provided by / (used in) investing activities 32,221 (100,339)
Financing Activities:    
Proceeds from public offering of common stock, net of issuance costs   93,796
Taxes paid related to net share settlement of equity awards (48)  
Proceeds from issuance of common stock 6,248 10,525
Claims settlement under Section 16(b) 14,452  
Net cash provided by financing activities 20,652 104,321
Net increase in cash and cash equivalents 28,257 1,019
Cash and cash equivalents, beginning of period 6,030 10,186
Cash and cash equivalents, end of period $ 34,287 $ 11,205