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Major Customers, Partnerships and Strategic Alliances (Tables)

3 Months Ended

Mar. 31, 2016

Biogen Inc [Member]

Research and Development Arrangement, Contract to Perform for Others [Line Items]

Revenues Recognized under Agreement

Revenues recognized under the agreement with Biogen for the three months ended March 31, 2016 and 2015 were as follows (in thousands):

		Three months ended
		March 31,
		2016				2015
Revenue related to Biogen Collaboration:
Recognition of upfront fee		$	608			$	1,523
Research services			2,031				1,533
Total		$	2,639			$	3,056

Shire AG [Member]

Research and Development Arrangement, Contract to Perform for Others [Line Items]

Revenues Recognized under Agreement

Revenues recognized under the agreement with Shire for the three months ended March 31, 2016 and 2015 were as follows (in thousands):

		Three months ended
		March 31,
		2016				2015
Revenue related to Shire Collaboration:
Recognition of upfront fee		$	542			$	542
Research services			429				4,522
Total		$	971			$	5,064

Sigma-Aldrich Corporation [Member]

Research and Development Arrangement, Contract to Perform for Others [Line Items]

Revenues Recognized under Agreement

Revenues recognized under the agreement with Sigma for the three months ended March 31, 2016 and 2015 were as follows (in thousands):

		Three months ended
		March 31,
		2016				2015
Revenue related to Sigma Collaboration:
Royalty revenues		$	12			$	264
License fee revenues			7				4,256
Total		$	19			$	4,520

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- Definition

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+ References

No definition available.

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- Definition

Tabular disclosure of contractual arrangements that involve two or more parties that both: (i) actively participate in a joint operating activity and (ii) are exposed to significant risks and rewards that depend on the commercial success of the joint operating activity. Additionally, the element may include all other transactions of the entity categorized collectively, if such comparison of collaborative arrangements as a component of all transactions of the entity is desired.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 808
-SubTopic 10
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6931272&loc=SL5834143-161434

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