<SEC-DOCUMENT>0001193125-16-787564-index.html : 20161207
<SEC-HEADER>0001193125-16-787564.hdr.sgml : 20161207
<ACCEPTANCE-DATETIME>20161207171556
ACCESSION NUMBER:		0001193125-16-787564
CONFORMED SUBMISSION TYPE:	424B5
PUBLIC DOCUMENT COUNT:		4
FILED AS OF DATE:		20161207
DATE AS OF CHANGE:		20161207

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SANGAMO BIOSCIENCES INC
		CENTRAL INDEX KEY:			0001001233
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				680359556
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-194126
		FILM NUMBER:		162039891

	BUSINESS ADDRESS:	
		STREET 1:		501 CANAL BLVD
		STREET 2:		POINT RICHMOND TECH CNTR.
		CITY:			RICHMOND
		STATE:			CA
		ZIP:			94804
		BUSINESS PHONE:		5109706000

	MAIL ADDRESS:	
		STREET 1:		501 CANAL BLVD
		STREET 2:		POINT RICHMOND TECH CNTR.
		CITY:			RICHMOND
		STATE:			CA
		ZIP:			94804
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B5
<SEQUENCE>1
<FILENAME>d270346d424b5.htm
<DESCRIPTION>424B5
<TEXT>
Document 1 - file: d270346d424b5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>g270346g03f28.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: g270346g03f28.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>g270346g56s59.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: g270346g56s59.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>g270346tx_logo.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: g270346tx_logo.jpg

</DOCUMENT>
</SEC-DOCUMENT>