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Income Taxes - Additional Information (Detail) - USD ($) | 1 Months Ended | 12 Months Ended
--- | --- | ---
Sep. 30, 2015 | Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2014
Income Taxes [Line Items] |  |  |  |
Federal statutory income tax rate |  | 34.00% |  |
Claim settlement received | $ 14,500,000 |  | $ 14,452,000 |
Settlement recognized as additional paid-in capital, net of tax |  |  | 9,495,000 |
Income tax benefit, claims settlement |  |  | 5,000,000 |
Increase in deferred tax assets valuation allowance |  | $ 23,800,000 | $ 5,000,000 | $ 9,800,000
Deferred tax assets, net operating loss carryforwards for federal |  | 412,000,000 |  |
Deferred tax assets, net operating loss carryforwards for state |  | 177,000,000 |  |
Federal research tax credit carryforwards |  | 9,700,000 |  |
State research tax credit carryforwards |  | $ 10,500,000 |  |
Tax credit carryforward, expiration year |  | 2018 |  |
Accrued interest and/or penalties |  | $ 0 |  |
State |  |  |  |
Income Taxes [Line Items] |  |  |  |
Operating loss carryforwards, expiration year |  | 2018 |  |
Federal |  |  |  |
Income Taxes [Line Items] |  |  |  |
Operating loss carryforwards, expiration year |  | 2018 |  |

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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible domestic operating loss carryforwards. Excludes state and local operating loss carryforwards. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 6 -URI http://asc.fasb.org/extlink&oid=65882285&loc=d3e32621-109319 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 25 -Paragraph 20 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=68052875&loc=d3e28680-109314 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 8 -URI http://asc.fasb.org/extlink&oid=65882285&loc=d3e32632-109319 + Details
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