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Major Customers, Partnerships and Strategic Alliances - Additional Information (Detail) |  | 1 Months Ended | 3 Months Ended | 6 Months Ended | 12 Months Ended
--- | --- | --- | --- | --- | ---
May 10, 2017 USD ($) | Jan. 31, 2014 USD ($) Program | Jun. 30, 2012 Targets | Jan. 31, 2012 USD ($) Targets | Jun. 30, 2017 USD ($) | Jun. 30, 2016 USD ($) | Jun. 30, 2017 USD ($) Product | Jun. 30, 2016 USD ($) | Dec. 31, 2014 USD ($)
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |  |
Number of research programs | Program |  | 2 |  |  |  |  |  |  |
Research and development |  |  |  |  | $ 14,984,000 | $ 19,454,000 | $ 27,926,000 | $ 34,720,000 |
Pfizer [Member] |  |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |  |
Revenues under agreement | $ 70,000,000 |  |  |  |  |  |  |  |
Milestone revenue receivable | 475,000,000 |  |  |  |  |  |  |  |
Milestone payments received |  |  |  |  |  |  | $ 0 |  |
Number of products approved | Product |  |  |  |  |  |  | 0 |  |
Royalty revenues |  |  |  |  |  |  | $ 0 |  |
Research program to develop laboratory research reagents |  |  |  |  |  |  | 32 months |  |
Deferred revenue |  |  |  |  | 66,200,000 |  | $ 66,200,000 |  |
Recognition of upfront fee |  |  |  |  | 3,800,000 |  |  |  |
Bioverativ Inc [Member] |  |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |  |
Revenues under agreement |  | $ 20,000,000 |  |  |  |  |  |  |
Milestone payments received |  |  |  |  |  |  | $ 0 |  |
Number of products approved | Product |  |  |  |  |  |  | 0 |  |
Royalty revenues |  |  |  |  |  |  | $ 0 |  |
Research program to develop laboratory research reagents |  |  |  |  |  |  | 44 months |  |
Deferred revenue |  |  |  |  | 5,500,000 |  | $ 5,500,000 |  |
Recognition of upfront fee |  |  |  |  | 442,000 | 608,000 | 884,000 | 1,216,000 |
Potential amount eligible to receive for certain milestones |  | 115,800,000 |  |  |  |  |  |  |
Potential amount to be funded for achievement of specified commercialized and sales milestones |  | 160,500,000 |  |  |  |  |  |  |
Bioverativ Inc [Member] | Sickle cell disease [Member] |  |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |  |
Milestone revenue receivable |  | 7,500,000 |  |  |  |  |  |  |
Bioverativ Inc [Member] | Beta-thalassemia Project [Member] |  |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |  |
Milestone revenue receivable |  | $ 6,000,000 |  |  |  |  |  |  |
Research and development |  |  |  |  | 2,900,000 | 2,100,000 | $ 4,500,000 | 4,100,000 |
Shire AG [Member] |  |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |  |
Revenues under agreement |  |  |  | $ 13,000,000 |  |  |  |  |
Research program to develop laboratory research reagents |  |  |  |  |  |  | 6 years |  |
Deferred revenue |  |  |  |  | 1,200,000 |  | $ 1,200,000 |  |
Recognition of upfront fee |  |  |  |  | 583,000 | 541,000 | 1,167,000 | 1,083,000 |
Research and development |  |  |  |  | $ 0 | $ 300,000 | $ 100,000 | $ 700,000 |
Aggregate number of gene targets | Targets |  |  |  | 7 |  |  |  |  |
Number of initial gene targets | Targets |  |  |  | 4 |  |  |  |  |
Number of gene targets | Targets |  |  | 5 |  |  |  |  |  |
Number of additional gene targets | Targets |  |  | 2 |  |  |  |  |  |
Recognition of milestone |  |  |  |  |  |  |  |  | $ 1,000,000
Maximum [Member] | SB-525 [Member] | Pfizer [Member] |  |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |  |
Milestone revenue receivable | 300,000,000 |  |  |  |  |  |  |  |
Maximum [Member] | Other Products [Member] | Pfizer [Member] |  |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |  |
Milestone revenue receivable | $ 175,000,000 |  |  |  |  |  |  |  |

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