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Property and Equipment - Summary of Property and Equipment (Detail) - USD ($) $ in Thousands	Dec. 31, 2017	Dec. 31, 2016
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	$ 16,367	$ 12,048
Less accumulated depreciation and amortization	(6,951)	(5,639)
Property and equipment, net	31,066	6,557
Laboratory equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	7,572	6,206
Furniture and fixtures [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	1,494	636
Leasehold improvements [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	3,425	1,330
Buildings [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	3,876	3,876
Construction in Progress [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, net	$ 21,650	$ 148

X

- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 360
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (c)
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-Publisher FASB
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-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.14)
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

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- Definition

Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

+ References

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+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
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-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
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-Subparagraph (SX 210.5-02(13))
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