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Marketable Securities - Schedule of Investments (Detail) - USD ($) $ in Thousands | Jun. 30, 2018 | Dec. 31, 2017
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Schedule Of Available For Sale Securities [Line Items] |  |
Cash equivalents, Amortized Cost | $ 59,406 | $ 49,826
Available-for-sale securities, Amortized Cost | 514,348 | 194,749
Available-for-sale securities, Gross Unrealized Gains | 110 |
Available-for-sale securities, Gross Unrealized (Losses) | (236) | (255)
Available-for-sale securities, Estimated Fair Value | 514,222 | 194,494
Total cash equivalents and available-for-sale securities, Amortized Cost | 571,489 | 223,634
Total cash equivalents and available-for-sale securities, Gross Unrealized Gains | 111 |
Total cash equivalents and available-for-sale securities, Gross Unrealized (Losses) | (236) | (255)
Total cash equivalents and available-for-sale securities, Estimated Fair Value | 571,364 | 223,379
Money market funds [Member] |  |
Schedule Of Available For Sale Securities [Line Items] |  |
Cash equivalents, Amortized Cost | 41,909 | 24,290
Cash equivalents, Estimated Fair Value | 41,909 | 24,290
Commercial paper securities [Member] |  |
Schedule Of Available For Sale Securities [Line Items] |  |
Cash equivalents, Amortized Cost | 15,232 | 4,595
Cash equivalents, Gross Unrealized Gains | 1 |
Cash equivalents, Estimated Fair Value | 15,233 | 4,595
Available-for-sale securities, Amortized Cost | 396,958 | 110,365
Available-for-sale securities, Gross Unrealized Gains | 110 |
Available-for-sale securities, Gross Unrealized (Losses) | (75) | (118)
Available-for-sale securities, Estimated Fair Value | 396,993 | 110,247
Cash equivalents [Member] |  |
Schedule Of Available For Sale Securities [Line Items] |  |
Cash equivalents, Amortized Cost | 57,141 | 28,885
Cash equivalents, Gross Unrealized Gains | 1 |
Cash equivalents, Estimated Fair Value | 57,142 | 28,885
Corporate debt securities [Member] |  |
Schedule Of Available For Sale Securities [Line Items] |  |
Available-for-sale securities, Amortized Cost | 98,834 | 75,886
Available-for-sale securities, Gross Unrealized (Losses) | (158) | (131)
Available-for-sale securities, Estimated Fair Value | 98,676 | 75,755
U.S. government sponsored entity debt securities [Member] |  |
Schedule Of Available For Sale Securities [Line Items] |  |
Available-for-sale securities, Amortized Cost | 18,556 | 8,498
Available-for-sale securities, Gross Unrealized (Losses) | (3) | (6)
Available-for-sale securities, Estimated Fair Value | $ 18,553 | $ 8,492

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