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Organization, Basis of Presentation and Summary of Significant Accounting Policies (Tables) | 6 Months Ended
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Jun. 30, 2018
Topic 606 [Member] |
Summary of Financial Statement Line Item Affected Cumulative Adjustment and Compared with Guidance in Effect Prior to Adoption | Refer below for a summary of the amount by which each financial statement line item was affected by the impact of the cumulative adjustment and as compared with the guidance that was in effect prior to the adoption:
|  | Impact of Topic 606 Adoption on Condensed Consolidated Balance Sheet as of January 1, 2018 |
(in thousands) |  | As reported under Topic 606 |  |  | Adjustments |  |  | Balances without adoption of Topic 606 |
Deferred revenue, current portion |  | $ | 29,626 |  |  | $ | 1,281 |  |  | $ | 28,345 |
Deferred revenue, noncurrent portion |  | $ | 26,846 |  |  | $ | (2,398 | ) |  | $ | 29,244 |
Accumulated deficit |  | $ | (494,362 | ) |  | $ | 1,117 |  |  | $ | (495,479 | )
|  | Impact of Topic 606 Adoption on Condensed Consolidated Balance Sheet as of June 30, 2018 |
(in thousands) |  | As reported under Topic 606 |  |  | Adjustments |  |  | Balances without adoption of Topic 606 |
Deferred revenue, current portion |  | $ | 57,215 |  |  | $ | 8,744 |  |  | $ | 65,959 |
Deferred revenue, noncurrent portion |  | $ | 137,731 |  |  | $ | (3,581 | ) |  | $ | 134,151 |
Accumulated deficit |  | $ | (531,189 | ) |  | $ | (5,163 | ) |  | $ | (536,352 | )
|  | Impact of Topic 606 Adoption on Condensed Consolidated Statement of Operations and Comprehensive Loss for the Three Months Ended June 30, 2018 |  |  | Impact of Topic 606 Adoption on Condensed Consolidated Statement of Operations and Comprehensive Loss for the Six Months Ended June 30, 2018 |
(in thousands) |  | As reported under Topic 606 |  |  | Adjustments |  |  | Balances without adoption of Topic 606 |  |  | As reported under Topic 606 |  |  | Adjustments |  |  | Balances without adoption of Topic 606 |
Collaboration revenue |  | $ | 21,289 |  |  | $ | (2,271 | ) |  | $ | 19,018 |  |  | $ | 33,840 |  |  | $ | (4,047 | ) |  | $ | 29,793 |
Net loss |  | $ | (16,640 | ) |  | $ | (2,271 | ) |  | $ | (18,911 | ) |  | $ | (36,827 | ) |  | $ | (4,047 | ) |  | $ | (40,874 | )
Net loss per share - basic and diluted: |  | $ | (0.17 | ) |  | $ | (0.02 | ) |  | $ | (0.19 | ) |  | $ | (0.40 | ) |  | $ | (0.04 | ) |  | $ | (0.44 | )
|  | Impact of Topic 606 Adoption on Condensed Consolidated Statement of Cash Flows for the Six Months Ended June 30, 2018 |
(in thousands) |  | As reported under Topic 606 |  |  | Adjustments |  |  | Balances without adoption of Topic 606 |
Net loss |  | $ | (36,827 | ) |  | $ | (4,047 | ) |  | $ | (40,874 | )
Changes in deferred revenue |  | $ | 138,474 |  |  | $ | 4,047 |  |  | $ | 142,521 |

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- Definition Tabular disclosure of the comparison between amounts disclosed under previous guidance and new guidance. + References No definition available. + Details
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