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Organization, Basis of Presentation and Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($) $ in Thousands | 9 Months Ended |  |  |  |
--- | --- | --- | --- | --- | ---
Sep. 30, 2018 | Sep. 30, 2017 | Jan. 01, 2018 | Dec. 31, 2017 | Nov. 30, 2017 | Dec. 31, 2016
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Liquid investments purchased with original maturities | three months or less |  |  |  |  |
Accumulated deficit | $ (544,032) |  |  | $ (495,479) |  |
Cash, cash equivalents, and restricted cash | 119,239 | $ 29,894 |  | 53,326 |  | $ 22,061
Restricted cash | 79,941 |  |  | $ 3,500 |  |
TxCell S.A. [Member] |  |  |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Restricted cash | 76,400 |  |  |  |  |
Brisbane Build-to-Suit Lease [Member] |  |  |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Restricted cash | 3,500 |  |  |  | $ 3,500 |
Topic 606 [Member] |  |  |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Accumulated deficit |  |  | $ (494,362) |  |  |
Topic 606 [Member] | Difference between Revenue Guidance in Effect before and after Topic 606 [Member] |  |  |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Accumulated deficit | (9,611) |  | 1,117 |  |  |
ASU 2016-18 [Member] |  |  |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Restricted cash balance |  |  | $ 3,500 |  |  |
Cash, cash equivalents, and restricted cash | $ 79,900 |  |  |  |  |
Pfizer [Member] | Customer Concentration Risk [Member] | Total revenues [Member] |  |  |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Percentage of revenues | 46.00% | 44.00% |  |  |  |
Kite Pharma, Inc. ("Kite") [Member] | Customer Concentration Risk [Member] | Total revenues [Member] |  |  |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Percentage of revenues | 29.00% |  |  |  |  |
Bioverativ Inc [Member] | Customer Concentration Risk [Member] | Total revenues [Member] |  |  |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Percentage of revenues |  | 39.00% |  |  |  |

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