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Organization, Basis of Presentation and Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Jan. 01, 2018	Dec. 31, 2017	Nov. 30, 2017	Dec. 31, 2016
Organization And Summary Of Significant Accounting Policies [Line Items]
Liquid investments purchased with original maturities	three months or less
Accumulated deficit	$ (544,032)			$ (495,479)
Cash, cash equivalents, and restricted cash	119,239	$ 29,894		53,326		$ 22,061
Restricted cash	79,941			$ 3,500
TxCell S.A. [Member]
Organization And Summary Of Significant Accounting Policies [Line Items]
Restricted cash	76,400
Brisbane Build-to-Suit Lease [Member]
Organization And Summary Of Significant Accounting Policies [Line Items]
Restricted cash	3,500				$ 3,500
Topic 606 [Member]
Organization And Summary Of Significant Accounting Policies [Line Items]
Accumulated deficit			$ (494,362)
Topic 606 [Member] | Difference between Revenue Guidance in Effect before and after Topic 606 [Member]
Organization And Summary Of Significant Accounting Policies [Line Items]
Accumulated deficit	(9,611)		1,117
ASU 2016-18 [Member]
Organization And Summary Of Significant Accounting Policies [Line Items]
Restricted cash balance			$ 3,500
Cash, cash equivalents, and restricted cash	$ 79,900
Pfizer [Member] | Customer Concentration Risk [Member] | Total revenues [Member]
Organization And Summary Of Significant Accounting Policies [Line Items]
Percentage of revenues	46.00%	44.00%
Kite Pharma, Inc. ("Kite") [Member] | Customer Concentration Risk [Member] | Total revenues [Member]
Organization And Summary Of Significant Accounting Policies [Line Items]
Percentage of revenues	29.00%
Bioverativ Inc [Member] | Customer Concentration Risk [Member] | Total revenues [Member]
Organization And Summary Of Significant Accounting Policies [Line Items]
Percentage of revenues		39.00%

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