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Quarterly Financial Data (Unaudited) - Summary of Quarterly Financial Data (Detail) - USD ($) $ / shares in Units, $ in Thousands | 3 Months Ended | 12 Months Ended
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Dec. 31, 2018 | Sep. 30, 2018 | Jun. 30, 2018 | Mar. 31, 2018 | Dec. 31, 2017 | Sep. 30, 2017 | Jun. 30, 2017 | Mar. 31, 2017 | Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016
Selected Quarterly Financial Information [Abstract] |  |  |  |  |  |  |  |  |  |  |
Revenues | $ 26,837 | $ 23,562 | $ 21,416 | $ 12,637 | $ 13,077 | $ 11,812 | $ 8,253 | $ 3,425 | $ 84,452 | $ 36,567 | $ 19,389
Expenses | 47,609 | 39,803 | 40,556 | 33,634 | 26,843 | 24,847 | 21,021 | 20,217 | 161,602 | 92,928 | 91,948
Net loss | (19,219) | (12,843) | (16,640) | (20,187) | (13,091) | (12,354) | (12,491) | (16,632) | (68,889) | (54,568) | (71,658)
Net loss attributable to non-controlling interest | (555) |  |  |  |  |  |  |  | (555) |  |
Net loss | $ (18,664) | $ (12,843) | $ (16,640) | $ (20,187) | $ (13,091) | $ (12,354) | $ (12,491) | $ (16,632) | $ (68,334) | $ (54,568) | $ (71,658)
Basic and diluted net loss per share attributable to Sangamo Therapeutics, Inc. stockholders | $ (0.18) | $ (0.13) | $ (0.17) | $ (0.23) | $ (0.15) | $ (0.15) | $ (0.17) | $ (0.23) | $ (0.70) | $ (0.70) | $ (1.02)

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