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Major Customers, Partnerships and Strategic Alliances (Tables)
 12 Months Ended
Dec. 31, 2018
Bioverativ Inc [Member]  
Research and Development Arrangement, Contract to Perform for Others [Line Items]  
Revenues Recognized under Agreement

Revenues recognized under the Bioverativ Agreement for the years ended December 31, 2018, 2017 and 2016 are as follows (in thousands):  

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Year Ended December 31,

 

 

 

2018

 

 

2017

 

 

2016

 

Revenue related to Bioverativ agreement:

 

 

 

 

 

 

 

 

 

 

 

 

Recognition of upfront fee

 

$

4,013

 

 

$

1,769

 

 

$

2,321

 

Research services

 

 

9,503

 

 

 

10,489

 

 

 

6,565

 

Total

 

$

13,516

 

 

$

12,258

 

 

$

8,886