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Marketable Securities - Summary of Cash Equivalents and Available-for-Sale Securities (Detail) - USD ($) $ in Thousands	Dec. 31, 2018	Dec. 31, 2017
Schedule Of Available For Sale Securities [Line Items]
Cash equivalents, Amortized Cost	$ 140,418	$ 49,826
Available-for-sale securities, Amortized Cost	259,974	194,749
Available-for-sale securities, Gross Unrealized (Losses)	(259)	(255)
Available-for-sale securities, Estimated Fair Value	259,715	194,494
Total cash equivalents and available-for-sale securities, Amortized Cost	363,265	223,634
Total cash equivalents and available-for-sale securities, Gross Unrealized (Losses)	(259)	(255)
Total cash equivalents and available-for-sale securities, Estimated Fair Value	363,006	223,379
Money market funds [Member]
Schedule Of Available For Sale Securities [Line Items]
Cash equivalents, Amortized Cost	103,291	24,290
Cash equivalents, Estimated Fair Value	103,291	24,290
Commercial paper securities [Member]
Schedule Of Available For Sale Securities [Line Items]
Cash equivalents, Amortized Cost		4,595
Cash equivalents, Estimated Fair Value		4,595
Available-for-sale securities, Amortized Cost	177,353	110,365
Available-for-sale securities, Gross Unrealized (Losses)	(129)	(118)
Available-for-sale securities, Estimated Fair Value	177,224	110,247
Cash equivalents [Member]
Schedule Of Available For Sale Securities [Line Items]
Cash equivalents, Amortized Cost	103,291	28,885
Cash equivalents, Estimated Fair Value	103,291	28,885
Corporate debt securities [Member]
Schedule Of Available For Sale Securities [Line Items]
Available-for-sale securities, Amortized Cost	63,981	75,886
Available-for-sale securities, Gross Unrealized (Losses)	(111)	(131)
Available-for-sale securities, Estimated Fair Value	63,870	75,755
U.S. government sponsored entity debt securities [Member]
Schedule Of Available For Sale Securities [Line Items]
Available-for-sale securities, Amortized Cost	18,640	8,498
Available-for-sale securities, Gross Unrealized (Losses)	(19)	(6)
Available-for-sale securities, Estimated Fair Value	$ 18,621	$ 8,492

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