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Property and Equipment, Net - Summary of Property and Equipment, Net (Detail) - USD ($) $ in Thousands	Dec. 31, 2018	Dec. 31, 2017
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	$ 22,822	$ 16,367
Less: accumulated depreciation and amortization	(9,310)	(6,951)
Property and equipment, net	78,723	31,066
Laboratory equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	11,466	7,572
Furniture and fixtures [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	3,840	1,494
Leasehold improvements [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	3,640	3,425
Buildings [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	3,876	3,876
Construction in progress [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, net	$ 65,211	$ 21,650

X

- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

+ References

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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