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Stockholders' Equity - Additional Information (Detail)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended
Jun. 22, 2015
shares
Apr. 30, 2018
USD ($)
$ / shares
shares
Jun. 30, 2017
USD ($)
$ / shares
shares
Dec. 31, 2018
USD ($)
Installment
$ / shares
shares
Dec. 31, 2017
USD ($)
$ / shares
shares
Dec. 31, 2016
USD ($)
$ / shares
shares
Nov. 10, 2017
shares
May 31, 2017
USD ($)
Dec. 07, 2016
USD ($)
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Preferred shares authorized       5,000,000          
Net proceeds from issuance of common stock, after deducting offering expenses | $       $ 215,758 $ 81,573        
Stock option maximum term       5 years 4 months 20 days          
Specified stockholder ownership percentage       10.00%          
Purchase price of common stock percent under stock incentive plans for specified stockholder       110.00%          
Stock option maximum term for specified stockholder       5 years          
Share of common stock subject to a stock option or stock appreciation right       100.00%          
Fixed ratio shares of common stock       1.33          
Additional equity award       3,115,078          
Intrinsic value of options exercised | $       $ 27,000 12,300 $ 100      
Options outstanding, Aggregate Intrinsic Value | $       24,468          
Options exercisable, Aggregate Intrinsic Value | $       12,702          
Options vested and expected to vest, aggregate intrinsic value | $       $ 24,500 71,700 0      
Restricted stock units awarded       346,055          
Total payments for the employees' tax obligations to taxing authorities | $       $ 254 $ 654 $ 776      
Share-Based Compensation Awards, Tranche 2 [Member]                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Stock options granted vesting percentage       0.33%          
Share-Based Compensation Awards, Tranche 3 [Member]                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Stock options granted vesting percentage       0.33%          
2013 Stock Incentive Plan [Member]                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Percent of fair value per share of common stock on option grant date       100.00%          
Stock options vesting period       4 years          
Stock options expiration term       10 years          
Stock reserved for issuance under plan       14,100,000          
Additional shares authorized under 2013 stock incentive plan 5,300,000     4,400,000          
Shares reserved for issuance of future awards       9,491,418          
2004 Stock Incentive Plan [Member]                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Stock reserved for issuance under plan       9,700,000          
Amended and Restated 2013 Stock Incentive Plan [Member]                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Stock reserved for issuance under plan             1,000,000    
Additional equity award   0              
2018 Stock Incentive Plan [Member]                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Percent of fair value per share of common stock on option grant date       100.00%          
Stock options vesting period       4 years          
Stock options expiration term       10 years          
Share of common stock subject to a stock option or stock appreciation right       100.00%          
Fixed ratio shares of common stock       1.33          
2010 Employee Stock Purchase Plan [Member]                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Percent of fair value per share of common stock on option grant date       85.00%          
Stock reserved for issuance under plan       4,600,000          
Purchase plan offering period       2 years          
Purchase plan purchase period       6 months          
Shares reserved for issuance of future awards       3,006,964          
Maximum [Member] | 2013 Stock Incentive Plan [Member]                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Stock option maximum term       10 years          
Maximum [Member] | 2018 Stock Incentive Plan [Member]                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Stock option maximum term       10 years          
Employee Stock Options [Member]                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Shares subject to repurchase rights       0          
Employee Stock Options [Member] | 2013 Stock Incentive Plan [Member]                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Share based vesting rights       Options granted under the 2013 Plan generally vest over four years at a rate of 25% one year from the grant date and one thirty-sixth per month thereafter and expire ten years after the grant, or earlier upon employment termination.          
Stock options granted vesting percentage       25.00%          
Employee Stock Options [Member] | 2018 Stock Incentive Plan [Member]                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Share based vesting rights       Generally, stock options granted under the 2018 Plan vest over four years at a rate of twenty-five percent (25%) on the one-year anniversary of the date of grant and one forty-eighth (1/48) per month thereafter and expire ten years after the date of grant, or earlier upon termination of employment or services to the Company          
Stock options granted vesting percentage       25.00%          
Restricted Stock Units (RSUs) [Member]                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Share based vesting rights       These awards generally vest as follows: one-third of the award will vest in a series of three successive equal annual installments.          
Restricted stock units awarded       346,055 12,600 60,000      
Grant date fair value per award of restricted stock units | $ / shares       $ 17.87 $ 15.85 $ 5.16      
Share-based compensation arrangement by share-based payment award, number of vesting installment | Installment       3          
Aggregate fair value of RSUs vested in period | $       $ 600 $ 1,200 $ 4,800      
Shares withheld from issuance in order to pay employee taxes       20,193 42,243 165,181      
Restricted Stock Units (RSUs) [Member] | Share-Based Compensation Awards, Tranche 1 [Member]                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Stock options granted vesting percentage       0.33%          
ATM Agreement [Member]                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Common stock issuable and sellable under offering agreement | $       $ 75,000       $ 75,000 $ 75,000
Common Stock [Member]                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Total shares issued   14,200,000 11,500,000 14,156,500 12,371,149        
Public offering price of common stock issued | $ / shares   $ 16.25 $ 7.25            
Net proceeds from issuance of common stock, after deducting offering expenses | $   $ 215,800 $ 78,100