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Quarterly Financial Data (Unaudited) - Summary of Quarterly Financial Data (Detail) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2018	Sep. 30, 2018	Jun. 30, 2018	Mar. 31, 2018	Dec. 31, 2017	Sep. 30, 2017	Jun. 30, 2017	Mar. 31, 2017	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Selected Quarterly Financial Information [Abstract]
Revenues	$ 26,837	$ 23,562	$ 21,416	$ 12,637	$ 13,077	$ 11,812	$ 8,253	$ 3,425	$ 84,452	$ 36,567	$ 19,389
Expenses	47,609	39,803	40,556	33,634	26,843	24,847	21,021	20,217	161,602	92,928	91,948
Net loss	(19,219)	(12,843)	(16,640)	(20,187)	(13,091)	(12,354)	(12,491)	(16,632)	(68,889)	(54,568)	(71,658)
Net loss attributable to non-controlling interest	(555)								(555)
Net loss	$ (18,664)	$ (12,843)	$ (16,640)	$ (20,187)	$ (13,091)	$ (12,354)	$ (12,491)	$ (16,632)	$ (68,334)	$ (54,568)	$ (71,658)
Basic and diluted net loss per share attributable to Sangamo Therapeutics, Inc. stockholders	$ (0.18)	$ (0.13)	$ (0.17)	$ (0.23)	$ (0.15)	$ (0.15)	$ (0.17)	$ (0.23)	$ (0.70)	$ (0.70)	$ (1.02)

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