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Cash and Marketable Securities - Summary of Cash Equivalents and Available-for-Sale Securities (Detail) - USD ($) $ in Thousands	Jun. 30, 2019	Dec. 31, 2018	Jun. 30, 2018	Dec. 31, 2017
Debt Securities, Available-for-sale [Line Items]
Cash equivalents, Amortized Cost	$ 169,222	$ 140,418	$ 59,406	$ 49,826
Available-for-sale securities, Amortized Cost	279,851	259,974
Available-for-sale securities, Gross Unrealized Gains	481	0
Available-for-sale securities, Gross Unrealized (Losses)	(5)	(259)
Available-for-sale securities, Estimated Fair Value	280,327	259,715
Total cash equivalents and available-for-sale securities, Amortized Cost	381,780	363,265
Total cash equivalents and available-for-sale securities, Gross Unrealized Gains	483	0
Total cash equivalents and available-for-sale securities, Gross Unrealized (Losses)	(5)	(259)
Total cash equivalents and available-for-sale securities, Estimated Fair Value	382,258	363,006
Money market funds
Debt Securities, Available-for-sale [Line Items]
Cash equivalents, Amortized Cost	71,490	103,291
Cash Equivalents, Gross Unrealized Gains	0	0
Cash Equivalents, Gross Unrealized (Losses)	0	0
Cash equivalents, Estimated Fair Value	71,490	103,291
Commercial paper securities
Debt Securities, Available-for-sale [Line Items]
Cash equivalents, Amortized Cost	30,439
Cash Equivalents, Gross Unrealized Gains	2
Cash Equivalents, Gross Unrealized (Losses)	0
Cash equivalents, Estimated Fair Value	30,441
Available-for-sale securities, Amortized Cost	170,598	177,353
Available-for-sale securities, Gross Unrealized Gains	355	0
Available-for-sale securities, Gross Unrealized (Losses)	0	(129)
Available-for-sale securities, Estimated Fair Value	170,953	177,224
Cash equivalents
Debt Securities, Available-for-sale [Line Items]
Cash equivalents, Amortized Cost	101,929	103,291
Cash Equivalents, Gross Unrealized Gains	2	0
Cash Equivalents, Gross Unrealized (Losses)	0	0
Cash equivalents, Estimated Fair Value	101,931	103,291
Corporate debt securities
Debt Securities, Available-for-sale [Line Items]
Available-for-sale securities, Amortized Cost	71,280	63,981
Available-for-sale securities, Gross Unrealized Gains	108	0
Available-for-sale securities, Gross Unrealized (Losses)	(5)	(111)
Available-for-sale securities, Estimated Fair Value	71,383	63,870
U.S. government-sponsored entity debt securities
Debt Securities, Available-for-sale [Line Items]
Available-for-sale securities, Amortized Cost	37,973	18,640
Available-for-sale securities, Gross Unrealized Gains	18	0
Available-for-sale securities, Gross Unrealized (Losses)	0	(19)
Available-for-sale securities, Estimated Fair Value	$ 37,991	$ 18,621

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