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Commitments and Contingencies - Additional Information (Detail)
$ in Millions
 3 Months Ended 6 Months Ended
Jun. 30, 2019
USD ($)
ft²
Mar. 31, 2019
Jun. 30, 2019
USD ($)
ft²
renewal_option
contract
Commitments And Contingencies [Line Items]      
Operating lease costs | $ $ 1.6   $ 2.8
Lease option to extend     true
Variable lease expense | $ $ 0.4   $ 0.6
Cash paid for operating lease liabilities included net cash used in operating activities | $     $ 1.1
Operating lease, weighted-average remaining lease term 9 years 3 months 18 days   9 years 3 months 18 days
Operating lease, weighted-average discount rate 6.90%   6.90%
Richmond Lease | Office and Laboratory      
Commitments And Contingencies [Line Items]      
Area of space leased (in sqft) 37,900   37,900
Richmond Lease | Operating Lease One | Research and Office Space      
Commitments And Contingencies [Line Items]      
Area of space leased (in sqft) 7,700   7,700
Lease expiration date     Aug. 31, 2019
Valbonne Lease      
Commitments And Contingencies [Line Items]      
Additional property available under lease | contract     2
Valbonne Lease | Operating Lease One | Research and Office Space      
Commitments And Contingencies [Line Items]      
Area of space leased (in sqft) 14,036   14,036
Valbonne Lease | Operating Lease Two | Office Space      
Commitments And Contingencies [Line Items]      
Area of space leased (in sqft) 6,800   6,800
Lease commencement date   Apr. 01, 2019  
Richmond and Valbonne Leases      
Commitments And Contingencies [Line Items]      
Lease option to extend     Certain of these leases also include renewal options at the election of the Company to renew or extend the lease for an additional five to ten years.
Richmond and Valbonne Leases | Minimum      
Commitments And Contingencies [Line Items]      
Lease agreement, extendable lease term 5 years   5 years
Richmond and Valbonne Leases | Maximum      
Commitments And Contingencies [Line Items]      
Lease agreement, extendable lease term 10 years   10 years
Brisbane Lease      
Commitments And Contingencies [Line Items]      
Remaining commencement, area of space leased (in sqft) 52,620   52,620
Expected lease commencement period     2019-06
Tenant improvement allowance | $ $ 6.8   $ 6.8
Lease not yet commenced, tenant improvement allowance | $ $ 10.2   $ 10.2
Number of lease term extension options | renewal_option     2
Brisbane Lease | Maximum      
Commitments And Contingencies [Line Items]      
Lease agreement, extendable lease term 5 years   5 years
Brisbane Lease | Office and Laboratory      
Commitments And Contingencies [Line Items]      
Area of space leased (in sqft) 87,700   87,700
Brisbane Lease | Office Space      
Commitments And Contingencies [Line Items]      
Commencement, area of space leased (in sqft) 35,080   35,080
Lease commencement period     2019-01